NF‐κB as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition

S Mirzaei, S Saghari, F Bassiri, R Raesi… - Journal of cellular …, 2022 - Wiley Online Library
Metastasis of tumor cells is a complex challenge and significantly diminishes the overall
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …

Harnessing Sulforaphane Potential as a Chemosensitizing Agent: A Comprehensive Review

BL Sailo, L Liu, S Chauhan, S Girisa, M Hegde, L Liang… - Cancers, 2024 - mdpi.com
Simple Summary Recent oncological research highlights the promising role of naturally
derived compounds in cancer prevention and treatment. Sulforaphane (SFN), a …

Anticancer activity of broccoli, its organosulfur and polyphenolic compounds

A Gasmi, A Gasmi Benahmed, M Shanaida… - Critical Reviews in …, 2023 - Taylor & Francis
The use of natural bioactive constituents from various food sources for anticancer purposes
has become increasingly popular worldwide. Broccoli (Brassica oleracea var. italica) is on …

[HTML][HTML] Predicting sulforaphane-induced adverse effects in colon cancer patients via in silico investigation

D Bozic, K Baralić, K Živančević, EA Miljaković… - Biomedicine & …, 2022 - Elsevier
Colorectal cancer (CRC) is a significant global health burden that ranks as the third most
diagnosed and second most common cause of cancer related deaths worldwide. New …

Reviewing the prospective pharmacological potential of isothiocyanates in fight against female-specific cancers

S Shoaib, FB Khan, MA Alsharif, MS Malik, SA Ahmed… - Cancers, 2023 - mdpi.com
Simple Summary Gynecological cancers are among the most commonly diagnosed cancers
in women globally. Despite advancements in diagnostics and treatments, these cancers …

Cationic lipid-assisted nanoparticles for simultaneous delivery of CD47 siRNA and R848 to promote antitumor immune responses

S Li, Y Chen, R Ma, Y Du, B Han - Frontiers in Pharmacology, 2023 - frontiersin.org
Introduction: Triple-negative breast cancer (TNBC) usually has a poor prognosis. Although
the immunotherapy of TNBC has achieved great progress, only a few patients can benefit …

Troponin T1 silencing inhibits paclitaxel resistance and the development of breast cancer via suppressing rat sarcoma virus/rapidly accelerated fibrosarcoma 1 …

T Zhu, P Zhou, L Yang, X Fang… - Environmental …, 2024 - Wiley Online Library
Objective We aimed to determine the role of Troponin T1 (TNNT1) in paclitaxel (PTX)
resistance and tumor progression in breast cancer (BC). Methods Differentially expressed …

Mechanisms of cell adhesion molecules in endocrine-related cancers: a concise outlook

Y Ruan, L Chen, D Xie, T Luo, Y Xu, T Ye… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy is a critical treatment for endocrine-related cancers; however,
chemoresistance and disease recurrence remain a challenge. The interplay between cancer …

Apigenin and its combination with Vorinostat induces apoptotic-mediated cell death in TNBC by modulating the epigenetic and apoptotic regulators and related …

S Nimal, N Kumbhar, Saruchi, S Rathore, N Naik… - Scientific Reports, 2024 - nature.com
Triple-negative breast cancer (TNBC) is a metastatic disease and a formidable treatment
challenge as it does not respond to existing therapies. Epigenetic regulators play a crucial …

[HTML][HTML] Introduced the ITGB1-DT as a novel biomarker associated with five potential drugs using bioinformatics analysis of breast cancer proteomics data and RT …

N Esfandiari, M Hashemi, K Hushmandi… - Molecular and Cellular …, 2023 - Elsevier
Background Breast cancer (BC) has been identified as a significant contributor to the rising
number of female cancer deaths. As, it has become clear that breast cancer development …