A facile approach synthesis of benzoylaryl benzimidazole as potential α-amylase and α-glucosidase inhibitor with antioxidant activity

LM Aroua, HR Almuhaylan, FM Alminderej… - Bioorganic …, 2021 - Elsevier
Synthetic routes to a series of benzoylarylbenzimidazol 3a-h have been derived from 3, 4-
diaminobenzophenone and an appropriate arylaldehyde in the presence of ammonium …

Diabetes-Related Mechanisms of Action Involved in the Therapeutic Effect of Croton Species: A Systematic Review

FA Espinoza-Hernandez, AD Moreno-Vargas… - Plants, 2023 - mdpi.com
Over the years, ethnopharmacological and phytochemical investigations have been
conducted to understand the potential effects of the Croton genus on several diseases. It has …

Profiling of phytochemicals from aerial parts of Terminalia neotaliala using LC-ESI-MS2 and determination of antioxidant and enzyme inhibition activities

MN Shahzad, S Ahmad, MI Tousif, I Ahmad, H Rao… - PloS one, 2022 - journals.plos.org
Objectives Owing to extraordinary healing power, Terminalia species have been used in
traditional medicine systems to treat various diseases. Many folklore uses of Terminalia …

Synthesis of novel benzimidazole-based thiazole derivatives as multipotent inhibitors of α-amylase and α-glucosidase: in vitro evaluation along with molecular …

R Hussain, S Iqbal, M Shah, W Rehman, S Khan… - Molecules, 2022 - mdpi.com
In this study, hybrid analogs of benzimidazole containing a thiazole moiety (1–17) were
afforded and then tested for their ability to inhibit α-amylase and α-glucosidase when …

Synthesis of azachalcones, their α-amylase, α-glucosidase inhibitory activities, kinetics, and molecular docking studies

F Saleem, KM Khan, S Chigurupati, M Solangi… - Bioorganic …, 2021 - Elsevier
Diabetes being a chronic metabolic disorder have attracted the attention of medicinal
chemists and biologists. The introduction of new and potential drug candidates for the cure …

Blue honeysuckle extracts retarded starch digestion by inhibiting glycosidases and changing the starch structure

X Zhang, R Rehman, S Wang, Y Ji, J Li, S Liu… - Food & Function, 2022 - pubs.rsc.org
Blue honeysuckle rich in anthocyanins can inhibit starch-digesting enzyme activity. This
study evaluated the inhibitory effect and mechanism of blue honeysuckle extract (BHE) on …

Synthesis of indole derivatives as diabetics II inhibitors and enzymatic kinetics study of α-glucosidase and α-amylase along with their in-silico study

M Taha, AS Alrashedy, NB Almandil, N Iqbal… - International Journal of …, 2021 - Elsevier
In this study, we have investigated a series of indole-based compounds for their inhibitory
study against pancreatic α-amylase and intestinal α-glucosidase activity. Inhibitors of …

Metabolite Profiling of Manilkara zapota L. Leaves by High-Resolution Mass Spectrometry Coupled with ESI and APCI and In Vitro Antioxidant Activity, α-Glucosidase …

S Islam, MB Alam, HJ Ann, JH Park, SH Lee… - International Journal of …, 2020 - mdpi.com
High-resolution mass spectrometry equipped with electrospray ionization (ESI) and
atmospheric pressure chemical ionization (APCI) sources was used to enhance the …

Mechanisms of action of Sri Lankan herbal medicines used in the treatment of diabetes: A review

DNAW Samarakoon, DI Uluwaduge… - Journal of integrative …, 2020 - Elsevier
Natural plant-based remedies for diabetes mellitus have been proven to be safe and
effective alternatives to Western medications, and details about more than 400 plants are …

[HTML][HTML] GC–MS profiling, phytochemical and biological investigation of aerial parts of Leucophyllum frutescens (Berl.) IM Johnst.(Cenizo)

I Ahmad, S Ahmed, EK Akkol, H Rao… - South African Journal of …, 2022 - Elsevier
Abstract Leucophyllum frutescens (Berl.) IM Johnst has been used as a crude drug for
treating various respiratory ailments, dysentery, cataract and liver disorders in the folk …