Cell‐Specific Actions of the Prostaglandin E‐Prostanoid Receptor 4 Attenuating Hypertension: A Dominant Role for Kidney Epithelial Cells Compared With …

T Yang, C Song, DL Ralph, P Andrews… - Journal of the …, 2022 - Am Heart Assoc
Background A beneficial role for prostanoids in hypertension is suggested by clinical studies
showing nonsteroidal anti‐inflammatory drugs, which block the production of all prostanoids …

Hypertension and human immunodeficiency virus: A paradigm for epithelial sodium channels?

KH Mutengo, SK Masenga, N Mwesigwa… - Frontiers in …, 2022 - frontiersin.org
Hypertension is a risk factor for end organ damage and death and is more common in
persons with HIV compared to the general population. Several mechanisms have been …

Genetic Deletion of AT1a Receptor or Na+/H+ Exchanger 3 Selectively in the Proximal Tubules of the Kidney Attenuates Two-Kidney, One-Clip Goldblatt …

XC Li, R Hassan, APO Leite, A Katsurada… - International journal of …, 2022 - mdpi.com
The roles of angiotensin II (Ang II) AT1 (AT1a) receptors and its downstream target Na+/H+
exchanger 3 (NHE3) in the proximal tubules in the development of two-kidney, 1-clip (2K1C) …

Novel Concepts in Nephron Sodium Transport: A Physiological and Clinical Perspective

JP Van Beusecum, F Rianto, J Teakell, V Kon… - Advances in Kidney …, 2023 - Elsevier
The kidneys play a critical role in maintaining total body sodium (Na+) balance across a
wide range of dietary intake, accomplished by a concerted effort involving multiple Na+ …