Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices
Mass spectrometry-based metabolomics approaches can enable detection and
quantification of many thousands of metabolite features simultaneously. However …
quantification of many thousands of metabolite features simultaneously. However …
How do plants defend themselves against pathogens-Biochemical mechanisms and genetic interventions
In agro-ecosystem, plant pathogens hamper food quality, crop yield, and global food
security. Manipulation of naturally occurring defense mechanisms in host plants is an …
security. Manipulation of naturally occurring defense mechanisms in host plants is an …
Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases
Y Chen, T Lu, U Pettersson-Kymmer, ID Stewart… - Nature …, 2023 - nature.com
Metabolic processes can influence disease risk and provide therapeutic targets. By
conducting genome-wide association studies of 1,091 blood metabolites and 309 metabolite …
conducting genome-wide association studies of 1,091 blood metabolites and 309 metabolite …
A reference map of potential determinants for the human serum metabolome
The serum metabolome contains a plethora of biomarkers and causative agents of various
diseases, some of which are endogenously produced and some that have been taken up …
diseases, some of which are endogenously produced and some that have been taken up …
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci
Few studies have explored the impact of rare variants (minor allele frequency< 1%) on
highly heritable plasma metabolites identified in metabolomic screens. The Finnish …
highly heritable plasma metabolites identified in metabolomic screens. The Finnish …
Multi-omics approaches to disease
High-throughput technologies have revolutionized medical research. The advent of
genotyping arrays enabled large-scale genome-wide association studies and methods for …
genotyping arrays enabled large-scale genome-wide association studies and methods for …
Metabolic analysis as a driver for discovery, diagnosis, and therapy
RJ DeBerardinis, KR Keshari - Cell, 2022 - cell.com
Metabolic anomalies contribute to tissue dysfunction. Current metabolism research spans
from organelles to populations, and new technologies can accommodate investigation …
from organelles to populations, and new technologies can accommodate investigation …
Multi-omics integration in biomedical research–A metabolomics-centric review
Recent advances in high-throughput technologies have enabled the profiling of multiple
layers of a biological system, including DNA sequence data (genomics), RNA expression …
layers of a biological system, including DNA sequence data (genomics), RNA expression …
MetaboAnalyst 3.0—making metabolomics more meaningful
J Xia, IV Sinelnikov, B Han, DS Wishart - Nucleic acids research, 2015 - academic.oup.com
Abstract MetaboAnalyst (www. metaboanalyst. ca) is a web server designed to permit
comprehensive metabolomic data analysis, visualization and interpretation. It supports a …
comprehensive metabolomic data analysis, visualization and interpretation. It supports a …
Cardiovascular metabolomics
RW McGarrah, SB Crown, GF Zhang, SH Shah… - Circulation …, 2018 - Am Heart Assoc
Disturbances in cardiac metabolism underlie most cardiovascular diseases. Metabolomics,
one of the newer omics technologies, has emerged as a powerful tool for defining changes …
one of the newer omics technologies, has emerged as a powerful tool for defining changes …