Building an ommatidium one cell at a time

JP Kumar - Developmental Dynamics, 2012 - Wiley Online Library
Since the discovery of a single white‐eyed male in a population of red eyed flies over 100
years ago (Morgan, 1910), the compound eye of the fruit fly, Drosophila melanogaster, has …

Principles of Drosophila eye differentiation

R Cagan - Current topics in developmental biology, 2009 - Elsevier
The Drosophila eye is one of nature's most beautiful structures and one of its most useful. It
has emerged as a favored model for understanding the processes that direct cell fate …

Tissue fluidity mediated by adherens junction dynamics promotes planar cell polarity-driven ommatidial rotation

N Founounou, R Farhadifar, GM Collu, U Weber… - Nature …, 2021 - nature.com
The phenomenon of tissue fluidity—cells' ability to rearrange relative to each other in
confluent tissues—has been linked to several morphogenetic processes and diseases, yet …

Medioapical contractile pulses coordinated between cells regulate Drosophila eye morphogenesis

C Rosa-Birriel, J Malin, V Hatini - Journal of Cell Biology, 2023 - rupress.org
Lattice cells (LCs) in the developing Drosophila retina change shape before attaining final
form. Previously, we showed that repeated contraction and expansion of apical cell contacts …

Hexagonal patterning of the Drosophila eye

RI Johnson - Developmental biology, 2021 - Elsevier
A complex network of transcription factor interactions propagates across the larval eye disc
to establish columns of evenly-spaced R8 precursor cells, the founding cells of Drosophila …

Long-term in vivo imaging of Drosophila larvae

P Kakanj, SA Eming, L Partridge, M Leptin - Nature Protocols, 2020 - nature.com
The Drosophila larva has been used to investigate many processes in cell biology, including
morphogenesis, physiology and responses to drugs and new therapeutic compounds …

p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis

RA Lang, K Herman, AB Reynolds… - …, 2014 - journals.biologists.com
Apical constriction (AC) is a widely utilized mechanism of cell shape change whereby
epithelial cells transform from a cylindrical to conical shape, which can facilitate …

[HTML][HTML] Preferential adhesion maintains separation of ommatidia in the Drosophila eye

S Bao, KF Fischbach, V Corbin, RL Cagan - Developmental biology, 2010 - Elsevier
In the Drosophila eye, neighboring ommatidia are separated by inter-ommatidial cells
(IOCs). How this ommatidial spacing emerges during eye development is not clear. Here we …

Cell adhesion in Drosophila: versatility of cadherin and integrin complexes during development

NA Bulgakova, B Klapholz, NH Brown - Current opinion in cell biology, 2012 - Elsevier
We highlight recent progress in understanding cadherin and integrin function in the model
organism Drosophila. New functions for these adhesion receptors continue to be discovered …

The WAVE regulatory complex and branched F-actin counterbalance contractile force to control cell shape and packing in the Drosophila eye

SJ Del Signore, R Cilla, V Hatini - Developmental cell, 2018 - cell.com
Contractile forces eliminate cell contacts in many morphogenetic processes. However,
mechanisms that balance contractile forces to promote subtler remodeling remain unknown …