The aggregation of proteins into amyloid fibrils and their deposition into plaques and
intracellular inclusions is the hallmark of amyloid disease. The accumulation and deposition …

Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …

The wall gives a Saccharomyces cerevisiae cell its osmotic integrity; defines cell shape
during budding growth, mating, sporulation, and pseudohypha formation; and presents …

Candida albicans and Staphylococcus aureus are often co-isolated in cases of biofilm-
associated infections. C. albicans can cause systemic disease through morphological switch …

Understanding the pathogenesis of an infectious disease is critical for developing new
methods to prevent infection and diagnose or cure disease. Adherence of microorganisms to …

Amyloid is a distinct β-sheet-rich fold that many proteins can acquire. Frequently associated
with neurodegenerative diseases in humans, including Alzheimer's, Parkinson's and …

In the past two decades, amyloids, typically associated with human diseases, have been
described to play various functional roles in nearly all life forms. The structural and functional …

Approximately two decades have passed since the description of the first gene in the
Candida albicans ALS (agglutinin-like sequence) family. Since that time, much has been …

The opportunistic fungal pathogen Candida albicans is capable of adhering to the oral
mucosa despite forces created by salivary flow. Although many fungal adhesion proteins …

Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis,
and Candida parapsilosis, are successful colonizers of a human host. Under certain …