A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury

EP Thelin, DW Nelson, BM Bellander - Acta neurochirurgica, 2017 - Springer
Background In order to improve injury assessment of brain injuries, protein markers of
pathophysiological processes and tissue fate have been introduced in the clinic. The most …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Serum neurofilament light protein predicts clinical outcome in traumatic brain injury

P Shahim, M Gren, V Liman, U Andreasson… - Scientific reports, 2016 - nature.com
Axonal white matter injury is believed to be a major determinant of adverse outcomes
following traumatic brain injury (TBI). We hypothesized that measurement of neurofilament …

Biomarkers for the diagnosis and prognosis of mild traumatic brain injury/concussion

CB Jeter, GW Hergenroeder, MJ Hylin… - Journal of …, 2013 - liebertpub.com
Mild traumatic brain injury (mTBI) results from a transfer of mechanical energy into the brain
from traumatic events such as rapid acceleration/deceleration, a direct impact to the head, or …

S100b as a prognostic biomarker in outcome prediction for patients with severe traumatic brain injury

A Goyal, MD Failla, C Niyonkuru, K Amin… - Journal of …, 2013 - liebertpub.com
As an astrocytic protein specific to the central nervous system, S100b is a potentially useful
marker in outcome prediction after traumatic brain injury (TBI). Some studies have …

Serum concentrations of ubiquitin C-terminal hydrolase-L1 and αII-spectrin breakdown product 145 kDa correlate with outcome after pediatric TBI

RP Berger, RL Hayes, R Richichi, SR Beers… - Journal of …, 2012 - liebertpub.com
Predicting outcome after pediatric traumatic brain injury (TBI) is important for providing
information to families and prescribing rehabilitation services. Previously published studies …

Biomarkers of hypoxic-ischemic encephalopathy in newborns

M Douglas-Escobar, MD Weiss - Frontiers in neurology, 2012 - frontiersin.org
As neonatal intensive care has evolved, the focus has shifted from improving mortality alone
to an effort to improve both mortality and morbidity. The most frequent source of neonatal …

Systematic review of clinical research on biomarkers for pediatric traumatic brain injury

L Papa, MM Ramia, JM Kelly, SS Burks… - Journal of …, 2013 - liebertpub.com
The objective was to systematically review the medical literature and comprehensively
summarize clinical research performed on biomarkers for pediatric traumatic brain injury …

Blood-based traumatic brain injury biomarkers–Clinical utilities and regulatory pathways in the United States, Europe and Canada

KK Wang, JC Munoz Pareja, S Mondello… - Expert review of …, 2021 - Taylor & Francis
Introduction Traumatic brain injury (TBI) is a major global health issue, resulting in
debilitating consequences to families, communities, and health-care systems. Prior research …

Group-based trajectory analysis applications for prognostic biomarker model development in severe TBI: a practical example

C Niyonkuru, AK Wagner, H Ozawa, K Amin… - Journal of …, 2013 - liebertpub.com
Over the last decade, biomarker research has identified potential biomarkers for the
diagnosis, prognosis, and management of traumatic brain injury (TBI). Several cerebrospinal …