Background Studies evaluating the role of midodrine as an adjunctive therapy to liberate
patients with shock from intravenous (IV) vasopressors have yielded mixed results. The aim …

Vasopressor dependence is a common problem affecting patients in the recovery phase of
critical illness, often necessitating intensive care unit (ICU) admission and other …

Introduction Intensive care unit (ICU) lengths of stay are modified by ongoing need for
haemodynamic support in critically ill patients. This is most commonly provided by …

Background: Midodrine has been used in the intensive care unit (ICU) setting to reduce the
time to vasopressor discontinuation. The limited data supporting midodrine use have led to …

To the Editor: After adequate fluid resuscitation, intravenous vasopressors (IVVs) are a
mainstay of therapy for patients experiencing shock. 1 Vasoplegia results in vascular …

Hypotension secondary to autonomic dysfunction is a common complication of acute spinal
cord injury (SCI) that may worsen neurologic outcomes. Midodrine, an enteral α-1 agonist, is …

Background: Sepsis is characterized as an infection that causes potentially fatal organ
malfunction as a result of a dysregulated patient response to the infection (SSC), with septic …

Conclusion Midodrine is a short-acting vasopressor approved by the FDA in 1996 for
orthostatic hypotension. It belongs to the drug class alpha-1-receptor agonist which …

Shock is a state of decreased organ perfusion that is life-threatening and requires emergent
medical intervention [1]. As such, patients who present with shock are often managed in the …