S100 is a broad subfamily of low-molecular weight calcium-binding proteins (9–14 kDa) with
structural similarity and functional discrepancy. It is required for inflammation and cellular …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder without a cure. Most
AD cases are sporadic where age represents the greatest risk factor. Lack of understanding …

The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …

S100 proteins are calcium-binding proteins that regulate several processes associated with
Alzheimer's disease (AD) but whose contribution and direct involvement in disease …

The Receptor for Advanced Glycation Endproducts (RAGE) is a multi-ligand receptor of the
immunoglobulin family. RAGE interacts with structurally different ligands probably through …

Background Multiple pathophysiological processes have been described in Alzheimer's
disease (AD). Their inter-individual variations, complex interrelations, and relevance for …

S100A6, also known as calcyclin, is a low-molecular-weight Ca2+-binding protein from the
S100 family that contains two EF-hands. S100A6 is expressed in a variety of mammalian …

Abstract Aims Reactive astrocytes in Alzheimer's disease (AD) have traditionally been
demonstrated by increased glial fibrillary acidic protein (GFAP) immunoreactivity; however …

Abstract Background Transcriptional studies suggest Alzheimer's disease (AD) involves
dysfunction of many cellular pathways, including synaptic transmission, cytoskeletal …

Alzheimer's disease (AD) is the most prevalent age‐related dementia affecting millions of
people worldwide. Its main pathological hallmark feature is the formation of insoluble protein …