Background: Red blood cell (RBC) transfusions are common in intensive care unit, trauma,
and surgical patients. However, the hematocrit that should be maintained in any particular …

Background Blood loss occurs significantly more frequently during total hip and knee
arthroplasty than among any other type of orthopedic operation, which can sometimes lead …

Whenever possible, the recommendations listed in this document are evidence based.
Articles reviewed in this guideline revision covered evidence from the past 10 years through …

Context Perioperative red blood cell transfusion is commonly used to address anemia, an
independent risk factor for morbidity and mortality after cardiac operations; however …

EXECUTIVE SUMMARY Since the initial 1996 American Thoracic Society (ATS) guideline
on nosocomial pneumonia, a number of new developments have appeared, mandating a …

Background—Intravascular red cell hemolysis impairs nitric oxide (NO)–redox homeostasis,
producing endothelial dysfunction, platelet activation, and vasculopathy. Red blood cell …

Background Stored red cells undergo progressive structural and functional changes over
time. We tested the hypothesis that serious complications and mortality after cardiac surgery …

Objective: Our objective was to quantify incremental risk associated with transfusion of
packed red blood cells and other blood components on morbidity after coronary artery …

Objective: To develop a clinical practice guideline for red blood cell transfusion in adult
trauma and critical care. Design: Meetings, teleconferences and electronic-based …

Although red blood cell (RBC) transfusions can be lifesaving, they are not without risk. In
critically ill patients, RBC transfusions are associated with increased morbidity and mortality …