Shaping the Nrf2-ARE-related pathways in Alzheimer's and Parkinson's diseases
L Fão, SI Mota, AC Rego - Ageing Research Reviews, 2019 - Elsevier
A failure in redox homeostasis is a common hallmark of Alzheimer's Disease (AD) and
Parkinson's Disease (PD), two age-dependent neurodegenerative disorders (NDD), causing …
Parkinson's Disease (PD), two age-dependent neurodegenerative disorders (NDD), causing …
Targeting microglial activation states as a therapeutic avenue in Parkinson's disease
SR Subramaniam, HJ Federoff - Frontiers in aging neuroscience, 2017 - frontiersin.org
Parkinson's disease (PD) is a chronic and progressive disorder characterized
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …
Neuroinflammation in neurological disorders: pharmacotherapeutic targets from bench to bedside
A Mishra, R Bandopadhyay, PK Singh, PS Mishra… - Metabolic Brain …, 2021 - Springer
Neuroinflammation is one of the host defensive mechanisms through which the nervous
system protects itself from pathogenic and or infectious insults. Moreover, neuroinflammation …
system protects itself from pathogenic and or infectious insults. Moreover, neuroinflammation …
Role of microglia in neurological disorders and their potentials as a therapeutic target
L Du, Y Zhang, Y Chen, J Zhu, Y Yang… - Molecular neurobiology, 2017 - Springer
Microglia are resident macrophage-like immune cells in the central nervous system (CNS)
and play a vital role in both physiological and pathological conditions, including restoring …
and play a vital role in both physiological and pathological conditions, including restoring …
[HTML][HTML] Microglial polarization: novel therapeutic strategy against ischemic stroke
Y Xue, D Nie, LJ Wang, HC Qiu, L Ma, MX Dong… - Aging and …, 2021 - ncbi.nlm.nih.gov
Ischemic stroke, which is the second highest cause of death and the leading cause of
disability, represents~ 71% of all strokes globally. Some studies have found that the key …
disability, represents~ 71% of all strokes globally. Some studies have found that the key …
Pharmacological targeting of microglial activation: new therapeutic approach
CY Liu, X Wang, C Liu, HL Zhang - Frontiers in Cellular Neuroscience, 2019 - frontiersin.org
Mounting evidence suggests that neuroinflammation is not just a consequence but a vital
contributor to the development and progression of Parkinson's disease (PD). Microglia in …
contributor to the development and progression of Parkinson's disease (PD). Microglia in …
Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation
Microglia are integral mediators of innate immunity within the mammalian central nervous
system. Typical microglial responses are transient, intending to restore homeostasis by …
system. Typical microglial responses are transient, intending to restore homeostasis by …
Anti-inflammatory activity of ursolic acid in MPTP-induced parkinsonian mouse model
SN Rai, W Zahra, SS Singh, H Birla, C Keswani… - Neurotoxicity …, 2019 - Springer
Neuroinflammation plays an important role in the progression of Parkinson's disease (PD)
and hence may represent a target for treatment. The drugs used currently for PD only …
and hence may represent a target for treatment. The drugs used currently for PD only …
Polydatin prevents lipopolysaccharide (LPS)-induced Parkinson's disease via regulation of the AKT/GSK3β-Nrf2/NF-κB signaling axis
B Huang, J Liu, T Meng, Y Li, D He, X Ran… - Frontiers in …, 2018 - frontiersin.org
Parkinson's disease (PD) is a common neurodegenerative disease characterized by
selective loss of dopaminergic neurons in the substantia nigra (SN). Neuroinflammation …
selective loss of dopaminergic neurons in the substantia nigra (SN). Neuroinflammation …
Natural phytochemicals as novel therapeutic strategies to prevent and treat Parkinson's disease: current knowledge and future perspectives
R Balakrishnan, S Azam, DY Cho… - Oxidative Medicine …, 2021 - Wiley Online Library
Parkinson's disease (PD) is the second‐most common neurodegenerative chronic disease
affecting both cognitive performance and motor functions in aged people. Yet despite the …
affecting both cognitive performance and motor functions in aged people. Yet despite the …