Single-virus tracking: from imaging methodologies to virological applications

SL Liu, ZG Wang, HY Xie, AA Liu, DC Lamb… - Chemical …, 2020 - ACS Publications
Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

Adenovirus entry: from infection to immunity

UF Greber, JW Flatt - Annual review of virology, 2019 - annualreviews.org
More than 80 different adenovirus (AdV) types infect humans through the respiratory, ocular,
or gastrointestinal tracts. They cause acute clinical mani-festations or persist under humoral …

Covalent labeling of nucleic acids

N Klöcker, FP Weissenboeck… - Chemical Society Reviews, 2020 - pubs.rsc.org
Labeling of nucleic acids is required for many studies aiming to elucidate their functions and
dynamics in vitro and in cells. Out of the numerous labeling concepts that have been …

Fluorescent dyes with large Stokes shifts for super-resolution optical microscopy of biological objects: a review

MV Sednev, VN Belov, SW Hell - Methods and applications in …, 2015 - iopscience.iop.org
The review deals with commercially available organic dyes possessing large Stokes shifts
and their applications as fluorescent labels in optical microscopy based on stimulated …

Innate immunity to adenovirus

R Hendrickx, N Stichling, J Koelen, L Kuryk… - Human gene …, 2014 - liebertpub.com
Human adenoviruses are the most widely used vectors in gene medicine, with applications
ranging from oncolytic therapies to vaccinations, but adenovirus vectors are not without side …

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

K Peng, W Muranyi, B Glass, V Laketa, SR Yant, L Tsai… - Elife, 2014 - elifesciences.org
The steps from HIV-1 cytoplasmic entry until integration of the reverse transcribed genome
are currently enigmatic. They occur in ill-defined reverse-transcription-and pre-integration …

Alkene–tetrazine ligation for imaging cellular DNA

U Rieder, NW Luedtke - Angewandte Chemie International …, 2014 - Wiley Online Library
Vinyl‐2′‐deoxyuridine (VdU) is the first reported metabolic probe for cellular DNA
synthesis that can be visualized by using an inverse electron demand Diels–Alder reaction …

Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection

M Rolot, AM Dougall, A Chetty, J Javaux… - Nature …, 2018 - nature.com
Infection with parasitic helminths can imprint the immune system to modulate bystander
inflammatory processes. Bystander or virtual memory CD8+ T cells (TVM) are non …

Viral and cellular interactions during adenovirus DNA replication

M Charman, C Herrmann, MD Weitzman - FEBS letters, 2019 - Wiley Online Library
Adenoviruses represent ubiquitous and clinically significant human pathogens, gene‐
delivery vectors, and oncolytic agents. The study of adenovirus‐infected cells has long been …

Principles of virus uncoating: cues and the snooker ball

Y Yamauchi, UF Greber - Traffic, 2016 - Wiley Online Library
Viruses are spherical or complex shaped carriers of proteins, nucleic acids and sometimes
lipids and sugars. They are metastable and poised for structural changes. These features …