Bacterial contamination of platelets for transfusion: strategies for prevention
Platelet transfusions carry greater risks of infection, sepsis, and death than any other blood
product, owing primarily to bacterial contamination. Many patients may be at particular risk …
product, owing primarily to bacterial contamination. Many patients may be at particular risk …
Pathogen‐reduced platelets for the prevention of bleeding
LJ Estcourt, R Malouf, S Hopewell… - Cochrane Database …, 2017 - cochranelibrary.com
Background Platelet transfusions are used to prevent and treat bleeding in people who are
thrombocytopenic. Despite improvements in donor screening and laboratory testing, a small …
thrombocytopenic. Despite improvements in donor screening and laboratory testing, a small …
Pathogen inactivation technologies for cellular blood components: an update
P Schlenke - Transfusion Medicine and Hemotherapy, 2014 - karger.com
Nowadays patients receiving blood components are exposed to much less transfusion-
transmitted infectious diseases than three decades before when among others HIV was …
transmitted infectious diseases than three decades before when among others HIV was …
Component pathogen inactivation: a critical review
CV Prowse - Vox sanguinis, 2013 - Wiley Online Library
Background and Objectives Pathogen inactivation (PI)‐treated plasma and platelets are
increasingly becoming the products of choice, where licensed. This review summarizes the …
increasingly becoming the products of choice, where licensed. This review summarizes the …
Proactive administration of platelets and plasma for patients with a ruptured abdominal aortic aneurysm: evaluating a change in transfusion practice
PI Johansson, J Stensballe, I Rosenberg… - …, 2007 - Wiley Online Library
BACKGROUND: Continued hemorrhage remains a major contributor of mortality in
massively transfused patients and those who survive have a higher platelet (PLT) count and …
massively transfused patients and those who survive have a higher platelet (PLT) count and …
Development of blood transfusion product pathogen reduction treatments: a review of methods, current applications and demands
V Salunkhe, PF Van der Meer, D de Korte… - … and Apheresis Science, 2015 - Elsevier
Transfusion-transmitted infections (TTI) have been greatly reduced in numbers due to the
strict donor selection and screening procedures, ie the availability of technologies to test …
strict donor selection and screening procedures, ie the availability of technologies to test …
Prophylactic platelet transfusion for prevention of bleeding in patients with haematological disorders after chemotherapy and stem cell transplantation
L Estcourt, S Stanworth, C Doree… - Cochrane Database …, 2012 - cochranelibrary.com
Background Platelet transfusions are used in modern clinical practice to prevent and treat
bleeding in thrombocytopenic patients with bone marrow failure. Although considerable …
bleeding in thrombocytopenic patients with bone marrow failure. Although considerable …
Hemovigilance monitoring of platelet septic reactions with effective bacterial protection systems
RJ Benjamin, T Braschler, T Weingand… - Transfusion, 2017 - Wiley Online Library
BACKGROUND Delayed, large‐volume bacterial culture and amotosalen/ultraviolet‐A light
pathogen reduction are effective at reducing the risk of bacterial proliferation in platelet …
pathogen reduction are effective at reducing the risk of bacterial proliferation in platelet …
Hemostatic efficacy of pathogen-inactivated vs untreated platelets: a randomized controlled trial
PF van der Meer, PF Ypma… - Blood, The Journal …, 2018 - ashpublications.org
Pathogen inactivation of platelet concentrates reduces the risk for blood-borne infections.
However, its effect on platelet function and hemostatic efficacy of transfusion is unclear. We …
However, its effect on platelet function and hemostatic efficacy of transfusion is unclear. We …
Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in people with haematological …
LJ Estcourt, SJ Stanworth, C Doree… - Cochrane Database …, 2015 - cochranelibrary.com
Background Platelet transfusions are used in modern clinical practice to prevent and treat
bleeding in people who are thrombocytopenic due to bone marrow failure. Although …
bleeding in people who are thrombocytopenic due to bone marrow failure. Although …