[HTML][HTML] Synthesis, biological evaluation and molecular docking study of pyrimidine based thiazolidinone derivatives as potential anti-urease and anti-cancer agents
Hybrid analogs containing molecules are always the choice of different synthetic researcher
due to their diverse biological applications and significantly more efficient. Heterocyclic …
due to their diverse biological applications and significantly more efficient. Heterocyclic …
Benzimidazole-based schiff base hybrid scaffolds: a promising approach to develop multi-target drugs for alzheimer's disease
A series of benzimidazole-based Schiff base derivatives (1–18) were synthesized and
structurally elucidated through 1H NMR, 13C NMR and HREI-MS analysis. Subsequently …
structurally elucidated through 1H NMR, 13C NMR and HREI-MS analysis. Subsequently …
[HTML][HTML] Bis-indole based triazine derivatives: Synthesis, characterization, in vitro β-glucuronidase anti-cancer and anti-bacterial evaluation along with in silico …
The present work described the synthetic procedure adopted for the synthesis of bis-indole-
based triazine derivatives via a series of reactions. All the compounds were synthesized …
based triazine derivatives via a series of reactions. All the compounds were synthesized …
Synthesis, acetylcholinesterase and butyrylcholinesterase inhibitory potential and molecular docking study of thiazole bearing thiourea analogues
We have synthesized fourteen thiazole bearing thiourea derivatives (1–14), characterized
through different techniques ie, NMR, HR-EIMS and tested against acetylcholinesterase and …
through different techniques ie, NMR, HR-EIMS and tested against acetylcholinesterase and …
Synthesis, in Vitro Bio-Evaluation and in Silico Molecular Docking Studies of Thiadiazole-Based Schiff Base Derivatives
Aim: Recently, thiadiazole-containing drugs have gained greater clinical relevance and are
being explored for the development of new antidiabetic, antiurease and antimicrobial agents …
being explored for the development of new antidiabetic, antiurease and antimicrobial agents …
New indole derivatives as multitarget anti-Alzheimer's agents: synthesis, biological evaluation and molecular dynamics
Background: Alzheimer's disease is a neurological disorder that causes brain cells to shrink
and die. Aim: Thirteen novel 'oxathiolanyl','pyrazolyl'and 'pyrimidinyl'indole derivatives were …
and die. Aim: Thirteen novel 'oxathiolanyl','pyrazolyl'and 'pyrimidinyl'indole derivatives were …
Design, Synthesis, and Molecular Docking Studies of Integrated Benzylidenethiazolidine‐2,4‐Dione and Thieno[2,3‐d]pyrimidine‐6‐Carboxylate Derivatives as …
B Nagaraju, M Rajeswari, N Vedasree, CA Rao… - …, 2023 - Wiley Online Library
The present work describes the synthesis of new series of 5‐arylidene‐thiazolidine‐2, 4‐
dione, thieno [2, 3‐d] pyrimidine‐6‐carboxylate derivatives 9 a–o. A variety of spectroscopic …
dione, thieno [2, 3‐d] pyrimidine‐6‐carboxylate derivatives 9 a–o. A variety of spectroscopic …
Thiosemicarbazone derivatives as potential inhibitors of acetylcholinesterase, butyrylcholinesterase and their molecular docking studies
AA AL-Zahrani, NS Awwad, HA Ibrahium… - Chemical Data …, 2023 - Elsevier
Alzheimer's disease (AD) is a well-known neurological disease that affects a lot of older
people around the world. Many single-targeted medicines that have reached clinical trials …
people around the world. Many single-targeted medicines that have reached clinical trials …
Nitrogen Doped Porous Biochar/β-CD-MOFs Heterostructures: Bi-Functional Material for Highly Sensitive Electrochemical Detection and Removal of Acetaminophen
Q Yu, J Zou, C Yu, G Peng, G Fan, L Wang, S Chen… - Molecules, 2023 - mdpi.com
Acetaminophen (AC) is one of the most common over-the-counter drugs, and its pollutant in
groundwater has attracted more attention due to its serious risk to human health. Currently …
groundwater has attracted more attention due to its serious risk to human health. Currently …
[HTML][HTML] Identification of 1, 2, 4-triazole-bearing Bis-Schiff base hybrid scaffolds: In vitro and in silico insights to develop promising anti-urease and anti-cancer agents
The present work describes the synthetic procedure of 1, 2, 4-triazole derivatives (1–14)
synthesized efficiently in a single step reaction. Basic skeleton confirmation was achieved …
synthesized efficiently in a single step reaction. Basic skeleton confirmation was achieved …