The hyaline cartilage is the most abundant type of cartilage in the body. It is responsible for
the bone formation in the embryo (endochondral ossification) and in adults, it can be found …

Osteoarthritis is a common joint disease for which there are currently no disease-modifying
drugs available. Degradation of the cartilage extracellular matrix is a central feature of the …

Organ-on-chip (OOC) systems recapitulate key biological processes and responses in vitro
exhibited by cells, tissues, and organs in vivo. Accordingly, these models of both health and …

Background Curcumin has been shown to have chondroprotective potential in vitro.
However, its effect on disease and symptom modification in osteoarthritis (OA) is largely …

Objective. The morphology of articular cartilage (AC) enables painless movement. Aging
and mechanical loading are believed to influence development of osteoarthritis (OA), yet the …

Articular cartilage is a highly specialised connective tissue of diarthrodial joints which
provides a smooth, lubricated surface for joint articulation and plays a crucial role in the …

Osteoarthritis (OA) is an age-related chronic progressive degenerative disease that induces
persistent pain and disabilities. The development of OA is a complex process, and the risk …

Avascular, aneural articular cartilage has a low capacity for self‐repair and as a
consequence is highly susceptible to degradative diseases such as osteoarthritis. Thus the …

The purpose of our study was to determine the association between biomechanical
outcomes of walking gait (peak vertical ground reaction force [vGRF], vGRF loading rate …

There is an urgent demand for long term solutions to improve osteoarthritis treatments in the
ageing population. There are drugs that control the pain but none that stop the progression …