Biocatalysis: enzymatic synthesis for industrial applications

S Wu, R Snajdrova, JC Moore… - Angewandte Chemie …, 2021 - Wiley Online Library
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Shortening synthetic routes to small molecule active pharmaceutical ingredients employing biocatalytic methods

S Simić, E Zukić, L Schmermund, K Faber… - Chemical …, 2021 - ACS Publications
Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …

[HTML][HTML] Biocatalysis making waves in organic chemistry

U Hanefeld, F Hollmann, CE Paul - Chemical Society Reviews, 2022 - pubs.rsc.org
Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

Power of biocatalysis for organic synthesis

CK Winkler, JH Schrittwieser, W Kroutil - ACS central science, 2021 - ACS Publications
Biocatalysis, using defined enzymes for organic transformations, has become a common
tool in organic synthesis, which is also frequently applied in industry. The generally high …

Biocatalysis as key to sustainable industrial chemistry

AR Alcántara, P Domínguez de María… - …, 2022 - Wiley Online Library
The role and power of biocatalysis in sustainable chemistry has been continuously brought
forward step by step to its present outstanding position. The problem‐solving capabilities of …

Enantioselective Transformations in the Synthesis of Therapeutic Agents

H Yang, H Yu, IA Stolarzewicz, W Tang - Chemical Reviews, 2023 - ACS Publications
The proportion of approved chiral drugs and drug candidates under medical studies has
surged dramatically over the past two decades. As a consequence, the efficient synthesis of …

(Chemo) biocatalytic upgrading of biobased furanic platforms to chemicals, fuels, and materials: a comprehensive review

N Li, MH Zong - ACS Catalysis, 2022 - ACS Publications
Biobased furans, such as furfural, 5-hydroxymethylfurfural, and 2, 5-furandicarboxylic acid,
are recognized as the top-value platform chemicals in the valorization of biomass to …

Photoenzymatic conversion of enamides to enantioenriched benzylic amines enabled by visible-light-induced single-electron reduction

J Zhang, Q Zhang, B Chen, J Yu, B Wang… - ACS Catalysis, 2023 - ACS Publications
The enantioselective reduction of enamides is an efficient and atom-economical way to
construct chiral amine motifs. In contrast to transition-metal complex based asymmetric …

Enzymatic late‐stage modifications: better late than never

E Romero, BS Jones, BN Hogg… - Angewandte Chemie …, 2021 - Wiley Online Library
Enzyme catalysis is gaining increasing importance in synthetic chemistry. Nowadays, the
growing number of biocatalysts accessible by means of bioinformatics and enzyme …

Enzyme immobilization in hydrogels: A perfect liaison for efficient and sustainable biocatalysis

J Meyer, LE Meyer, S Kara - Engineering in Life Sciences, 2022 - Wiley Online Library
Biocatalysis is an established chemical synthesis technology that has by no means been
restricted to research laboratories. The use of enzymes for organic synthesis has evolved …