Circular RNAs: promising biomarkers for human diseases

Z Zhang, T Yang, J Xiao - EBioMedicine, 2018 - thelancet.com
Circular RNA (circRNA) is a group of endogenous noncoding RNA characterized by a
covalently closed cyclic structure lacking poly-adenylated tails. Recent studies have …

[HTML][HTML] Circular RNAs in cancer

DH Bach, SK Lee, AK Sood - Molecular Therapy-Nucleic Acids, 2019 - cell.com
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …

A systemic review on tuberculosis

A Natarajan, PM Beena, AV Devnikar, S Mali - Indian Journal of …, 2020 - Elsevier
Tuberculosis (TB), which is caused by bacteria of the Mycobacterium tuberculosis complex,
is one of the oldest diseases known to affect humans and a major cause of death worldwide …

[HTML][HTML] Circular RNAs in immune responses and immune diseases

X Chen, T Yang, W Wang, W Xi, T Zhang, Q Li… - Theranostics, 2019 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are novel clusters of endogenous noncoding RNAs (ncRNAs) that
are widely expressed in eukaryotic cells. In contrast to the generation of linear RNA …

Circular RNAs: expression, localization, and therapeutic potentials

Q Yang, F Li, AT He, BB Yang - Molecular therapy, 2021 - cell.com
Circular RNAs (circRNAs) are RNAs with a unique circular structure that is generated from
back-splicing processes. These circular molecules were discovered more than 40 years ago …

Circular RNAs and gastrointestinal cancers: epigenetic regulators with a prognostic and therapeutic role

P Naeli, MH Pourhanifeh, MR Karimzadeh… - Critical reviews in …, 2020 - Elsevier
Both environmental and genetic factors are involved in the initiation and development of
gastrointestinal cancer. Covalent closed circular RNAs (circRNAs) are produced by a …

The potential of using blood circular RNA as liquid biopsy biomarker for human diseases

G Wen, T Zhou, W Gu - Protein & cell, 2021 - academic.oup.com
Circular RNA (circRNA) is a novel class of single-stranded RNAs with a closed loop
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …

Circular RNAs: promising molecular biomarkers of human aging-related diseases via functioning as an miRNA sponge

S Ren, P Lin, J Wang, H Yu, T Lv, L Sun… - … Therapy Methods & …, 2020 - cell.com
Circular RNAs (circRNAs) are a new class of noncoding single-stranded RNAs that differ
from linear microRNAs (miRNAs), since they form covalently closed loop structures without …

Functions of circular RNA in human diseases and illnesses

A Gu, DK Jaijyan, S Yang, M Zeng, S Pei, H Zhu - Non-coding RNA, 2023 - mdpi.com
Circular RNAs (circRNAs) represent single-stranded RNA species that contain covalently
closed 3′ and 5′ ends that provide them more stability than linear RNA, which has free …

Lariat intronic RNAs in the cytoplasm of vertebrate cells

GJS Talhouarne, JG Gall - Proceedings of the National …, 2018 - National Acad Sciences
Most intronic RNAs are degraded within seconds or minutes after their excision from newly
formed transcripts. However, stable intronic sequence RNAs (sisRNAs) have been …