Multiple sclerosis (MS) is a neurologic disease affecting myelinated nerves in the central
nervous system (CNS). The disease often debuts as a clinically isolated syndrome, eg, optic …

Purpose of review This review will examine the current evidence that genetic and/or
epigenetic variation may influence the multiple sclerosis (MS) clinical course, phenotype …

Multiple sclerosis risk has a well-established polygenic component, yet the genetic
contribution to disease course and severity remains unclear and difficult to examine …

Background Multiple sclerosis (MS) causes chronic inflammation and demyelination of the
central nervous system and comprises a class of neurodegenerative diseases in which …

Objective: In a previous pilot monocentric study, we investigated the relation between
human leukocyte antigen (HLA) genotype and multiple sclerosis (MS) disease progression …

Background: The genetic predisposition to multiple sclerosis (MS) is associated with HLA
alleles, especially HLA-DRB1* 15: 01. Objective: To identify associations between findings …

Background HLA genes are the most polymorphic of the human genome and have distinct
allelic frequencies in populations of different geographical regions of the world, serving as …

Özet Multipl skleroz hastalığı tedavisine yeni ajanların girmesi ile yeni tedavi modelleri
oluşmuş (basamaklı tedavi-indüksiyon tedavisi) ve ilaçların artan etkinliği beraberinde ilaç …

Methods: 184 patient subjects who had been definitively diagnosed with MS, based on the
McDonald criteria, and 105 healthy subjects with a similar age and gender profile were …

Multiple sclerosis (MS) is a chronic and inflammatory disease of the central nervous system
(CNS) that is common in people between the ages of 20 and 40. Although the exact cause of …