Brain-derived neurotrophic factor: Regulation, effects, and potential clinical relevance
EE Benarroch - Neurology, 2015 - AAN Enterprises
Brain-derived neurotrophic factor (BDNF) is the most ubiquitous and intensively studied
member of the family of neurotrophins in the CNS. The transcriptional regulation of BDNF is …
member of the family of neurotrophins in the CNS. The transcriptional regulation of BDNF is …
Multigenerational and transgenerational effects of paternal exposure to drugs of abuse on behavioral and neural function
LR Goldberg, TJ Gould - European Journal of Neuroscience, 2019 - Wiley Online Library
Addictions are highly heritable disorders, with heritability estimates ranging from 39% to
72%. Multiple studies suggest a link between paternal drug abuse and addiction in their …
72%. Multiple studies suggest a link between paternal drug abuse and addiction in their …
Microstructural white matter biomarkers of symptom severity and therapy outcome in catatonia: Rationale, study design and preliminary clinical data of the whiteCAT …
D Hirjak, GA Brandt, R Peretzke, S Fritze… - Schizophrenia …, 2024 - Elsevier
The number of magnetic resonance imaging (MRI) studies on neuronal correlates of
catatonia has dramatically increased in the last 10 years, but conclusive findings on white …
catatonia has dramatically increased in the last 10 years, but conclusive findings on white …
16p11. 2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro
Reciprocal copy number variations (CNVs) of 16p11. 2 are associated with a wide spectrum
of neuropsychiatric and neurodevelopmental disorders. Here, we use human induced …
of neuropsychiatric and neurodevelopmental disorders. Here, we use human induced …
The role of irisin in Alzheimer's disease
OY Kim, J Song - Journal of clinical medicine, 2018 - mdpi.com
Alzheimer's disease (AD) is characterized by progressive memory dysfunction, oxidative
stress, and presence of senile plaques formed by amyloid beta (Aβ) accumulation in the …
stress, and presence of senile plaques formed by amyloid beta (Aβ) accumulation in the …
Lateral hypothalamic control of the ventral tegmental area: reward evaluation and the driving of motivated behavior
SM Tyree, L de Lecea - Frontiers in systems neuroscience, 2017 - frontiersin.org
The lateral hypothalamus (LH) plays an important role in many motivated behaviors, sleep-
wake states, food intake, drug-seeking, energy balance, etc. It is also home to a …
wake states, food intake, drug-seeking, energy balance, etc. It is also home to a …
[HTML][HTML] Multigenerational epigenetic inheritance: One step forward, two generations back
JJ Tuscher, JJ Day - Neurobiology of Disease, 2019 - Elsevier
Modifications to DNA and histone proteins serve a critical regulatory role in the developing
and adult brain, and over a decade of research has established the importance of these …
and adult brain, and over a decade of research has established the importance of these …
Treadmill exercise mitigates neuroinflammation and increases BDNF via activation of SIRT1 signaling in a mouse model of T2DM
X Lang, N Zhao, Q He, X Li, X Li, C Sun, X Zhang - Brain Research Bulletin, 2020 - Elsevier
Although previous studies showed that exercise can improve cognitive dysfunction in type 2
diabetes (T2DM), the underlying mechanism remains unclear. Sirtuin 1 (SIRT1) has been …
diabetes (T2DM), the underlying mechanism remains unclear. Sirtuin 1 (SIRT1) has been …
Effects of the FNDC5/Irisin on elderly dementia and cognitive impairment
J Peng, J Wu - Frontiers in aging neuroscience, 2022 - frontiersin.org
Population aging is an inevitable problem nowadays, and the elderly are going through a lot
of geriatric symptoms, especially cognitive impairment. Irisin, an exercise-stimulating …
of geriatric symptoms, especially cognitive impairment. Irisin, an exercise-stimulating …
Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome
Methamphetamine (Meth) abuse has reached epidemic proportions in many countries and
can induce psychotic episodes mimicking the clinical profile of schizophrenia. Brain-derived …
can induce psychotic episodes mimicking the clinical profile of schizophrenia. Brain-derived …