Evaluation of outcomes in patients receiving amantadine to improve alertness after traumatic Brain injury

RM Hadgu, A Borghol, C Gillard, C Wilson… - Hospital …, 2021 - journals.sagepub.com
Background: Amantadine has been used off-label to improve alertness after traumatic brain
injury (TBI). The goal of this study is to assess the mean change at 72 hours and in course of …

Dual Neurostimulant Therapy May Optimize Acute Neurorecovery for Severe Traumatic Brain Injuries

BM Tracy, ME Silverman, C Cordero-Caballero… - Journal of Surgical …, 2021 - Elsevier
Background Neurostimulants (NS) can be used to treat patients with a traumatic brain injury
(TBI) with altered levels of consciousness. We sought to determine if amantadine alone …

Saxagliptin for Disorders of Consciousness: AI, Retrospective Observations, and Preclinical Data

D Toker, J Chiang, P Vespa, C Schnakers, MM Monti - 2024 - researchsquare.com
Despite advancements in the neuroscience of consciousness, no new effective medications
for disorders of consciousness (DOC), such as coma or vegetative state, have been …

Effects of preoperative intravenous amantadine sulfate infusion on wake up test duration and postoperative opioid consumption in adolescents undergoing spine …

GM Aboelfadl, S Elsawy, BO Elnady… - Perioperative Care and …, 2021 - Elsevier
Background Amantadine sulfate is both a dopamine agonist and N-methyle-D-Aspartate
(NMDA) antagonist which can augment the levels of dopamine in the striate body by …

Evaluation of the Effect of Modafinil on Respiratory and Cerebral Outcomes after Coronary Artery Bypass Graft Surgery

M Mansouri, G Massoumi… - ARYA Atherosclerosis …, 2022 - arya.mui.ac.ir
BACKGROUND: Pulmonary complications following cardiopulmonary bypass (CPB) pump
during coronary artery bypass grafting (CABG) are relatively common and the incidence of …