Ever since its invention half a century ago, flow cytometry has been a major tool for single‐
cell analysis, fueling advances in our understanding of a variety of complex cellular systems …

The inherent heterogeneity in cell populations has become of great interest and importance
as analytical techniques have improved over the past decades. With the advent of …

From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

Direct lineage reprogramming represents a remarkable conversion of cellular and
transcriptome states,,. However, the intermediate stages through which individual cells …

Advances in single-cell mass cytometry have increasingly improved highly multidimensional
characterization of immune cell heterogeneity. The immunoassay multiplexing capacity …

Forced expression of reprogramming factors can convert somatic cells into induced
pluripotent stem cells (iPSCs). Here we studied genome topology dynamics during …

Single-cell analysis provides insights into cellular heterogeneity and dynamics of individual
cells. This Feature highlights recent developments in key analytical techniques suited for …

Differentiating somatic cells are progressively restricted to specialized functions during
ontogeny, but they can be experimentally directed to form other cell types, including those …

The ability to reprogram somatic cells into induced pluripotent stem cells (iPSCs) using
defined factors provides new tools for biomedical research. However, some iPSC clones …

To understand how the immune system works, one needs to have a clear picture of its
cellular compositon and the cells' corresponding properties and functionality. Mass …