Understanding the evolutionary and ecological roles of'non-genetic'inheritance (NGI) is
daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights …

In eukaryotes, DNA is packaged into chromatin, which presents significant barriers to
transcription. Non-histone chromatin proteins such as the Heterochromatin Protein 1 (HP1) …

The eukaryotic genome is packaged into transcriptionally active euchromatin and silent
heterochromatin, with most studies focused on the former encompassing the majority of …

Transposable elements (TEs) must replicate in germline cells to pass novel insertions to
offspring. In Drosophila melanogaster ovaries, TEs can exploit specific developmental …

Transposable elements (TEs) are selfish genetic parasites that increase their copy number
at the expense of host fitness. The 'success', or genome-wide abundance, of TEs differs …

Coevolution between transposable elements (TEs) and their hosts can be antagonistic,
where TEs evolve to avoid silencing and the host responds by reestablishing TE …

HP1 proteins are essential for establishing and maintaining transcriptionally silent
heterochromatin. They dimerize, forming a binding interface to recruit diverse chromatin …

Heterochromatin is a gene-poor and repeat-rich genomic compartment ubiquitously found in
eukaryotes. Despite its low transcriptional activity, heterochromatin plays important roles in …

HP1 proteins bind dynamically to H3K9 methylation and are essential for establishing and
maintaining transcriptionally silent epigenetic states, known as heterochromatin. HP1 …

Transposable elements (TEs) must replicate in germline cells to pass novel insertions to
offspring. In Drosophila melanogaster ovaries, TEs can exploit specific developmental …