Platelets have long been known for their role in hemostasis. In this, platelet adhesion and
activation leads to the formation of a firm thrombus and thus the sealing of a damaged blood …

Psoriasis is a chronic inflammatory skin disease with a prevalence of 0.14% to 1.99%. The
underlying pathology is mainly driven by the abnormal immune responses including …

A state-of-the-art lecture titled “novel mechanisms of thrombo-inflammation during infection”
was presented at the ISTH Congress in 2022. Platelet, neutrophil, and endothelial cell …

Beamline I22 at Diamond Light Source is dedicated to the study of soft-matter systems from
both biological and materials science. The beamline can operate in the range 3.7 keV to 22 …

New findings highlight the complex interplay of innate immunity, coagulation and platelets in
inflammation and infection, and unravel novel molecular pathways and effector functions …

Blood clot formation induced by dysfunctional coagulation is a frequent complication of
coronavirus disease 2019 (COVID-19) and a high-risk factor for severe illness and death …

Antimicrobial peptides (AMPs) have been investigated for their potential use as an
alternative to antibiotics due to the increased demand for new antimicrobial agents. AMPs …

Traditionally, platelets have been exclusively considered for their procoagulant and
antifibrinolytic effects during normal activation of hemostasis. Effectively, activated platelets …

Inflammation is a life-saving immune reaction occurring in response to invading pathogens.
Nonetheless, inflammation can also occur in an uncontrolled, unrestricted manner, leading …

Platelets are central players in thrombosis and hemostasis but are increasingly recognized
as key components of the immune system. They shape ensuing immune responses by …