[HTML][HTML] Regulation of intestinal barrier function by microbial metabolites

S Ghosh, CS Whitley, B Haribabu, VR Jala - Cellular and molecular …, 2021 - Elsevier
The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …

[HTML][HTML] Polyphenol-mediated gut microbiota modulation: toward prebiotics and further

MC Rodríguez-Daza, EC Pulido-Mateos… - Frontiers in …, 2021 - frontiersin.org
The genome of gut microbes encodes a collection of enzymes whose metabolic functions
contribute to the bioavailability and bioactivity of unabsorbed (poly) phenols. Datasets from …

Bioactivity of dietary polyphenols: The role of metabolites

SV Luca, I Macovei, A Bujor, A Miron… - Critical reviews in …, 2020 - Taylor & Francis
A polyphenol-rich diet protects against chronic pathologies by modulating numerous
physiological processes, such as cellular redox potential, enzymatic activity, cell proliferation …

Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway

R Singh, S Chandrashekharappa, SR Bodduluri… - Nature …, 2019 - nature.com
The importance of gut microbiota in human health and pathophysiology is undisputable.
Despite the abundance of metagenomics data, the functional dynamics of gut microbiota in …

Ellagic acid and intestinal microflora metabolite urolithin A: A review on its sources, metabolic distribution, health benefits, and biotransformation

M Zhang, S Cui, B Mao, Q Zhang, J Zhao… - Critical reviews in …, 2023 - Taylor & Francis
Foods rich in ellagic tannins are first hydrolyzed into ellagic acid in the stomach and small
intestine, and then converted into urolithins with high bioavailability by the intestinal flora …

Recent advances in the production and applications of ellagic acid and its derivatives. A review

DD Evtyugin, S Magina, DV Evtuguin - Molecules, 2020 - mdpi.com
Ellagitannins (ETs), characterized by their diversity and chemical complexity, belong to the
class of hydrolysable tannins that, via hydrolysis under acidic or alkaline conditions, can …

Biomarkers and utility of the antioxidant potential of probiotic Lactobacilli and Bifidobacteria as representatives of the human gut microbiota

OV Averina, EU Poluektova, MV Marsova… - Biomedicines, 2021 - mdpi.com
Lactobacilli and bifidobacteria are an important part of human gut microbiota. Among
numerous benefits, their antioxidant properties are attracting more and more attention …

The bioactivity and applications of pomegranate peel extract: A review

Q Xiang, M Li, J Wen, F Ren, Z Yang… - Journal of Food …, 2022 - Wiley Online Library
Pomegranate peel (PP) is a by‐product in the processing of pomegranate products, which is
usually discarded as a waste. However, a large number of researches have shown that …

[HTML][HTML] Why is it important to understand the nature and chemistry of tannins to exploit their potential as nutraceuticals?

S Molino, MP Francino, JÁR Henares - Food research international, 2023 - Elsevier
Tannins comprise a large group of polyphenols that can differ widely in chemical
composition and molecular weight. The use of tannins dates back to antiquity, but it is only in …

Polyphenols as Drivers of a Homeostatic Gut Microecology and Immuno-Metabolic Traits of Akkermansia muciniphila: From Mouse to Man

MC Rodríguez-Daza, WM de Vos - International Journal of Molecular …, 2022 - mdpi.com
Akkermansia muciniphila is a mucosal symbiont considered a gut microbial marker in
healthy individuals, as its relative abundance is significantly reduced in subjects with gut …