It is now well accepted that many tumors undergo a process of clonal selection which means
that tumor antigens arising at various stages of tumor progression are likely to be …

Uveal melanoma (UM) and retinoblastoma (RB), which cause blindness and even death,
are the most frequently observed primary intraocular malignancies in adults and children …

Uveal melanoma (UM) is the most common intraocular malignancy in adults. So far, no
systemic therapy or standard treatment exists to reduce the risk of metastasis and improve …

Simple Summary Uveal melanoma is the most common primary intraocular malignancy in
adults. Unfortunately, metastasis develops in up to 50% of cases and outcomes are poor for …

Simple Summary Despite improvements in the early identification and successful control of
primary uveal melanoma, 50% of patients will develop metastatic disease with only marginal …

Solid tumors including skin, lung, breast, colon, and prostate cancers comprise the most
diagnosed cancers worldwide. Treatment of such cancers is still challenging specially in the …

Background: Uveal melanoma (UM) is a rare subtype of melanoma that generally has a poor
prognosis once it has metastasized. Clinical trials evaluating immune checkpoint inhibitors …

Abstract Purpose of Review Uveal melanoma is a distinct subtype of melanoma
characterized by a unique biology and divergent response to immune therapies. In this …

There have been rapid advancements in the field of ocular oncology for the diagnosis and
management of intraocular, adnexal, and orbital tumors. Targeted therapy is in the forefront …

Metastatic melanoma remains the deadliest form of skin cancer. Immune checkpoint
inhibition (ICI) immunotherapy has defined a new age in melanoma treatment, but …