Recent policy changes have led to significant increases in the use of cannabis for both
medical and recreational purposes. Although men are more likely to endorse past month …

Cannabis is the second most frequently used substance in the world and regulated or
legalized for recreational use in Canada and fourteen US states and territories. As with all …

Introduction: Despite known sex differences in the endocannabinoid system of animals, little
attention has been paid to sex differences in human's cannabis use patterns and effects. The …

Background The use of medical cannabis is increasing, most commonly for pain, anxiety
and depression. Emerging data suggest that use and abuse of prescription drugs may be …

Microglia, the resident immune cells of the brain, can take on a range of pro-or anti-
inflammatory phenotypes to maintain homeostasis. However, the sustained activation of pro …

Despite the exponential increase in fear research during the last years, few studies have
included female subjects in their design. The need to include females arises from the …

Abstract Δ9-tetrahydrocannabinol (THC) is the intoxicating constituent of cannabis and is
responsible for the drug's reinforcing effects. Retrospective human studies suggest that …

Background Women exhibit an accelerated progression from first cannabis use to cannabis
use disorder (CUD) and show pronounced negative clinical issues related to CUD relative to …

Alzheimer's disease (AD) is a debilitating neurodegenerative disease characterized by
declining cognition and behavioral impairment, and hallmarked by extracellular amyloid-β …

Abstract Purpose of the Review Cannabis is the most commonly used illicit substance
worldwide. In recent decades, highly concentrated products have flooded the market, and …