Dermatophytes are the aetiological factors of a majority of superficial fungal infections. What
distinguishes them from other pathogenic filamentous fungi is their unique ability to degrade …

Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …

The burden of fungal infections is not widely appreciated. Although these infections are
responsible for over one million deaths annually, it is estimated that one billion people are …

Antifungal resistance has become prevalent worldwide. Understanding the factors involved
in spread of resistance allows the formulation of strategies to slow resistance development …

Introduction There is an epidemic emergence of increased resistance in dermatophytes with
to antifungal drugs with ergosterol1 (Erg1) and Erg11 mutations to terbinafine and azoles …

Treating fungal infections is challenging and frequently requires long-term courses of
antifungal drugs. Considering the limited number of existing antifungal drugs, it is crucial to …

Spliceosomal introns are noncoding sequences that are spliced from pre-mRNA. They are
ubiquitous in eukaryotic genomes, although the average number of introns per gene varies …

The increasing prevalence of dermatophyte resistance to terbinafine, a key drug in the
treatment of dermatophytosis, represents a significant obstacle to treatment. Trichophyton …

Alternative splicing is a common but complex posttranscriptional regulatory process in
eukaryotes, through which multiple different transcripts are produced from a single pre …

Genomes of strains of the zoophilic dermatophyte Microsporum canis from invasive
(disseminated and subcutaneous) and noninvasive (tinea capitis) infections were compared …