Cognitively driven pupil modulations reflect certain underlying brain functions. What do
these reflections tell us? Here, we review findings that have identified key roles for three …

Pathological alterations to the locus coeruleus, the major source of noradrenaline in the
brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI …

Events associated with aversive or rewarding outcomes are prioritized in memory. This
memory boost is commonly attributed to the elicited affective response, closely linked to …

This review aims to synthesise a large pre-clinical and clinical literature related to a
hypothesised role of the locus coeruleus norepinephrine system in responses to acute and …

Arousal level changes constantly and it has a profound influence on performance during
everyday activities. Fluctuations in arousal are regulated by the autonomic nervous system …

The long-term fate of a memory is not exclusively determined by the events occurring at the
moment of encoding. Research at the cellular, circuit, and behavioral levels is beginning to …

Vagus nerve stimulation (VNS) is widely used to treat drug-resistant epilepsy and
depression. While the precise mechanisms mediating its long-term therapeutic effects are …

We rely on our long-term memories to guide future behaviors, making it adaptive to prioritize
the retention of goal-relevant, salient information in memory. In this review, we discuss …

Our daily lives unfold continuously, yet when we reflect on the past, we remember those
experiences as distinct and cohesive events. To understand this phenomenon, early …

Neuromelanin-sensitive MRI (NM-MRI) purports to detect the content of neuromelanin (NM),
a product of dopamine metabolism that accumulates with age in dopamine neurons of the …