[HTML][HTML] Mucins in the mucosal barrier to infection

SK Linden, P Sutton, NG Karlsson, V Korolik… - Mucosal …, 2008 - Elsevier
The mucosal tissues of the gastrointestinal, respiratory, reproductive, and urinary tracts, and
the surface of the eye present an enormous surface area to the exterior environment. All of …

Sialic acids as regulators of molecular and cellular interactions

R Schauer - Current opinion in structural biology, 2009 - Elsevier
The wide occurrence of sialic acids (Sia) in various chemical forms linked as monomers or
polymers in an outstanding position in a multitude of complex carbohydrates of animals and …

Experimental models to study intestinal microbes–mucus interactions in health and disease

L Etienne-Mesmin, B Chassaing… - FEMS microbiology …, 2019 - academic.oup.com
ABSTRACT A close symbiotic relationship exists between the intestinal microbiota and its
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …

Microbial adhesins to gastrointestinal mucus

N Juge - Trends in microbiology, 2012 - cell.com
The gastrointestinal tract (GIT) is lined by a layer of mucus formed by mucin glycoproteins.
This layer constitutes a physical and chemical barrier between the intestinal contents and …

Immunological Perspective: Helicobacter pylori Infection and Gastritis

H Yang, B Hu - Mediators of inflammation, 2022 - Wiley Online Library
Helicobacter pylori is a spiral‐shaped gram‐negative bacterium. Its infection is mainly
transmitted via oral‐oral and fecal‐oral routes usually during early childhood. It can achieve …

Helicobacter pylori BabA–SabA Key Roles in the Adherence Phase: The Synergic Mechanism for Successful Colonization and Disease Development

D Doohan, YAA Rezkitha, LA Waskito, Y Yamaoka… - Toxins, 2021 - mdpi.com
Helicobacter pylori is a pathogenic microorganism that successfully inhabits the human
stomach, colonizing it by producing several virulence factors responsible for preventing host …

Rotavirus interactions with host intestinal epithelial cells

JO Amimo, SA Raev, J Chepngeno… - Frontiers in …, 2021 - frontiersin.org
Rotavirus (RV) is the foremost enteric pathogen associated with severe diarrheal illness in
young children (< 5years) and animals worldwide. RV primarily infects mature enterocytes in …

[HTML][HTML] Exploring alternative treatments for Helicobacter pylori infection

G Ayala, WI Escobedo-Hinojosa… - World journal of …, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is a successful pathogen that can persist in the stomach of an
infected person for their entire life. It provokes chronic gastric inflammation that leads to the …

MUC1 Limits Helicobacter pylori Infection both by Steric Hindrance and by Acting as a Releasable Decoy

SK Lindén, YH Sheng, AL Every, KM Miles… - PLoS …, 2009 - journals.plos.org
The bacterium Helicobacter pylori can cause peptic ulcer disease, gastric adenocarcinoma
and MALT lymphoma. The cell-surface mucin MUC1 is a large glycoprotein which is highly …

Sweet-talk: role of host glycosylation in bacterial pathogenesis of the gastrointestinal tract

AP Moran, A Gupta, L Joshi - Gut, 2011 - gut.bmj.com
Glycosylation is a key modification of proteins and lipids and is involved in most
intermolecular and intercellular interactions. The gastrointestinal mucus gel is continuous …