The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …

The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …

Triple-negative breast cancer (TNBC) is a subtype of breast cancer (BC) with the most
aggressive phenotype and poor overall survival. Using bioinformatics tools, we identified …

Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …

Endometrial cancer (EC) has been classified over the years, for prognostic and therapeutic
purposes. In recent years, classification systems have been emerging not only based on EC …

In contrast to primary colorectal cancer (CRC) little is known about the genomic landscape of
metastasized CRC. Here we present whole genome sequencing data of metastases of 429 …

MicroRNAs (miRNAs) are a class of small non-coding RNAs ranging from 17 to 25 nt in
length. miR-637 is down-regulated in most cancers and up-regulated only in clear cell renal …

MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …

The Human Genome Project led to the discovery that about 80% of our DNA is transcribed in
RNA molecules. Only 2% of the human genome is translated into proteins, the rest mostly …

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer (BC) with a
poor prognosis. To date, the mechanism of TNBC's aggressive phenotype is still unclear …