The rodent hippocampus generates new neurons throughout life. This process, named adult
hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the …

Neural stem cells (NSCs) generate new neurons throughout life in the mammalian brain.
Adult-born neurons shape brain function, and endogenous NSCs could potentially be …

Multimodal astrocyte–neuron communications govern brain circuitry assembly and function.
For example, through rapid glutamate release, astrocytes can control excitability, plasticity …

Synapses between engram cells are believed to be substrates for memory storage, and the
weakening or loss of these synapses leads to the forgetting of related memories. We found …

The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

Cognitive dysfunction and reactive microglia are hallmarks of traumatic brain injury (TBI), yet
whether these cells contribute to cognitive deficits and secondary inflammatory pathology …

The dentate gyrus of the mammalian hippocampus continuously generates new neurons
during adulthood. These adult-born neurons become functionally active and are thought to …

Adult hippocampal neurogenesis plays a critical role in memory and emotion processing,
and this process is dynamically regulated by neural circuit activity. However, it remains …

Throughout life, new neurons are continuously added to the dentate gyrus. As this
continuous addition remodels hippocampal circuits, computational models predict that …

Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …