Pathogenicity and virulence of malaria: Sticky problems and tricky solutions

IS Walker, SJ Rogerson - Virulence, 2023 - Taylor & Francis
Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Asymptomatic malaria in the clinical and public health context

J Cheaveau, DC Mogollon, MAN Mohon… - Expert review of anti …, 2019 - Taylor & Francis
Introduction: Historically, the global community has focused on the control of symptomatic
malaria. However, interest in asymptomatic malaria has been growing, particularly in the …

Sources of persistent malaria transmission in a setting with effective malaria control in eastern Uganda: a longitudinal, observational cohort study

C Andolina, JC Rek, J Briggs, J Okoth… - The Lancet Infectious …, 2021 - thelancet.com
Background Symptomatic malaria cases reflect only a small proportion of all Plasmodium
spp infections. Many infected individuals are asymptomatic, and persistent asymptomatic …

The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density

HC Slater, A Ross, I Felger, NE Hofmann… - Nature …, 2019 - nature.com
Malaria infections occurring below the limit of detection of standard diagnostics are common
in all endemic settings. However, key questions remain surrounding their contribution to …

Assessment of ultra-sensitive malaria diagnosis versus standard molecular diagnostics for malaria elimination: an in-depth molecular community cross-sectional study

NE Hofmann, M Gruenberg, E Nate, A Ura… - The Lancet infectious …, 2018 - thelancet.com
Background Submicroscopic malaria infections contribute to transmission in exposed
populations but their extent is underestimated even by standard molecular diagnostics …

Sex-based differences in clearance of chronic Plasmodium falciparum infection

J Briggs, N Teyssier, JI Nankabirwa, J Rek… - Elife, 2020 - elifesciences.org
Multiple studies have reported a male bias in incidence and/or prevalence of malaria
infection in males compared to females. To test the hypothesis that sex-based differences in …

[HTML][HTML] Plasmodium vivax gametocytes and transmission

S Bantuchai, H Imad, W Nguitragool - Parasitology International, 2022 - Elsevier
Malaria elimination means cessation of parasite transmission. At present, the declining
malaria incidence in many countries has made elimination a feasible goal. Transmission …

Genotyping cognate Plasmodium falciparum in humans and mosquitoes to estimate onward transmission of asymptomatic infections

KM Sumner, E Freedman, L Abel, A Obala… - Nature …, 2021 - nature.com
Malaria control may be enhanced by targeting reservoirs of Plasmodium falciparum
transmission. One putative reservoir is asymptomatic malaria infections and the scale of their …

[HTML][HTML] The prevention and treatment of Plasmodium vivax malaria

CS Chu, NJ White - PLoS medicine, 2021 - journals.plos.org
The prevention and treatment of Plasmodium vivax malaria | PLOS Medicine Skip to main
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Transmission risk beyond the village: entomological and human factors contributing to residual malaria transmission in an area approaching malaria elimination on …

HM Edwards, P Sriwichai, K Kirabittir, J Prachumsri… - Malaria journal, 2019 - Springer
Background A mixed methods study was conducted to look at the magnitude of residual
malaria transmission (RMT) and factors contributing to low (< 1% prevalence), but sustained …