Decellularized matrices in regenerative medicine

DA Taylor, LC Sampaio, Z Ferdous, AS Gobin, LJ Taite - Acta biomaterialia, 2018 - Elsevier
Of all biologic matrices, decellularized extracellular matrix (dECM) has emerged as a
promising tool used either alone or when combined with other biologics in the fields of tissue …

[HTML][HTML] Neural tissue engineering with structured hydrogels in CNS models and therapies

J George, CC Hsu, LTB Nguyen, H Ye, Z Cui - Biotechnology advances, 2020 - Elsevier
The development of techniques to create and use multiphase microstructured hydrogels
(granular hydrogels or microgels) has enabled the generation of cultures with more …

A controlled design of aligned and random nanofibers for 3D bi-functionalized nerve conduits fabricated via a novel electrospinning set-up

JI Kim, TI Hwang, LE Aguilar, CH Park, CS Kim - Scientific reports, 2016 - nature.com
Scaffolds made of aligned nanofibers are favorable for nerve regeneration due to their
superior nerve cell attachment and proliferation. However, it is challenging not only to …

A novel GelMA-pHEMA hydrogel nerve guide for the treatment of peripheral nerve damages

TD Usal, D Yucel, V Hasirci - International journal of biological …, 2019 - Elsevier
Damage to the nervous system due to age, diseases or trauma may inhibit signal transfer
along the nervous system. Nerve guides are used to treat these injuries by bridging the …

Sustained release of growth factors from photoactivated platelet rich plasma (PRP)

G Irmak, TT Demirtaş, M Gümüşderelioğlu - European Journal of …, 2020 - Elsevier
The goal of this study is to specify the ability of polychromatic light source (PAC), providing
effective wavelengths in the range of 600–1200 nm (near-infrared region, NIR), to activate …

Regeneration of rat sciatic nerve using PLGA conduit containing rat ADSCs with controlled release of BDNF and gold nanoparticles

M Jahromi, S Razavi, R Seyedebrahimi, P Reisi… - Journal of Molecular …, 2021 - Springer
Implantation of a nerve guidance conduit (NGC) carrying neuroprotective factors is
promising for repairing peripheral nerve injury. Here, we developed a novel strategy for …

Adipose tissue stem cells in peripheral nerve regeneration—In vitro and in vivo

SC Rhode, JP Beier, T Ruhl - Journal of neuroscience research, 2021 - Wiley Online Library
After peripheral nerve injury, Schwann cells (SCs) are crucially involved in several steps of
the subsequent regenerative processes, such as the Wallerian degeneration. They promote …

Electrospinning of small diameter vascular grafts with preferential fiber directions and comparison of their mechanical behavior with native rat aortas

C Grasl, M Stoiber, M Röhrich, F Moscato… - Materials Science and …, 2021 - Elsevier
Conventional electrospun small diameter vascular grafts have a random fiber orientation. In
order to achieve mechanical characteristics similar to a native blood vessel, a controllable …

An optimized collagen-fibrin blend engineered neural tissue promotes peripheral nerve repair

CMAP Schuh, AGE Day, H Redl… - Tissue Engineering Part …, 2018 - liebertpub.com
Tissue engineering approaches in nerve regeneration often aim to improve results by
bridging nerve defects with conduits that mimic key features of the nerve autograft. One such …

Characterization and biological evaluation of new PLGA/fibrin/lignin biocomposite electrospun scaffolds

M Norouzi, M Rafienia, S Hosseini - Physica Scripta, 2023 - iopscience.iop.org
In this study, we produced electrospun scaffolds from 10% pure PLGA solution, and 10%
polyblend solutions of PLGA/Fibrin, PLGA/Lignin, and PLGA/Fibrin/Lignin with proportions of …