Adaptable hydrogels have recently emerged as a promising platform for three‐dimensional
(3D) cell encapsulation and culture. In conventional, covalently crosslinked hydrogels …

Receptor-ligand bonds strengthened by tensile mechanical force are referred to as catch
bonds. This review examines experimental data and biophysical theory to analyze why …

INTRODUCTION Cadherins are an ancient class of transmembrane proteins that are
essential for the formation of multicellular tissues in metazoans. Cadherins link intercellular …

Vinculin is an actin-binding protein thought to reinforce cell-cell and cell-matrix adhesions.
However, how mechanical load affects the vinculin–F-actin bond is unclear. Using a single …

Binding of integrins to ligands provides anchorage and signals for the cell, making them
prime candidates for mechanosensing molecules. How force regulates integrin–ligand …

Ligand–receptor interactions that are reinforced by mechanical stress, so-called catch-
bonds, play a major role in cell–cell adhesion. They critically contribute to widespread …

Classical cadherin cell-cell adhesion proteins play key morphogenetic roles during
development and are essential for maintaining tissue integrity in multicellular organisms …

Pterodactylane is a [4]-ladderane with substituents on the central rung. Comparing the
mechanochemistry of the [4]-ladderane structure when pulled from the central rung versus …

Mechanotransduction at cell–cell adhesions is crucial for the structural integrity,
organization, and morphogenesis of epithelia. At cell–cell junctions, ternary E-cadherin/β …

Haemostasis in the arteriolar circulation mediated by von Willebrand factor (VWF) binding to
platelets is an example of an adhesive interaction that must withstand strong hydrodynamic …