The dose of opioid prescribed for postoperative pain relief has traditionally been based on
the weight of the patient. Although a reduction in dose is often suggested for elderly patients …

This pilot study evaluated the efficacy and side effects of a combination of initial patient-
controlled analgesia (PCA) for dose-finding with transdermal fentanyl administration. Twenty …

BACKGROUND/PURPOSE: Intravenous patient-controlled analgesia (IVPCA) is one of the
most widely used postoperative analgesic methods. Many factors could affect the total …

It is often asserted that older patients are more sensitive to opioid analgesics than younger
patients but experimental evidence for this assertion remains sparse. Two studies were …

Objective The aim of this study was to characterize the relationship between morphine
plasma concentration and repeated time to postoperative remedication events in children …

Intermittent parenteral bolus doses of morphine are commonly used for postoperative
analgesia. Morphine is typically given by intramuscular or intravenous injection but there are …

A range of self‐administered demand doses of morphine (0.4, 0.7 and 1.0 mg) were
prescribed to supplement a fixed‐rate infusion (1.5 mg/hour) for pain control after …

Pain is a common occurrence for the hospitalized elder, and may often be under recognized
and inadequately managed. Insufficient pain management can lead to the sequelae of …

It is common knowledge among specialists that strong opioids play a major role in cancer
pain management, and over the last years many reports supporting this opinion have been …

Postoperative pain is an expected result of a surgical procedure, and is an undesirable
sensory and affective experience related to tissue trauma or disease processes …