Intestinal 'infant-type'bifidobacteria mediate immune system development in the first 1000 days of life

C Lin, Y Lin, H Zhang, G Wang, J Zhao, H Zhang… - Nutrients, 2022 - mdpi.com
Immune system maturation begins early in life, but few studies have examined how early-life
gut microbiota colonization educates the neonatal immune system. Bifidobacteria …

Bifidobacterium bifidum: A Key Member of the Early Human Gut Microbiota

F Turroni, S Duranti, C Milani, GA Lugli… - Microorganisms, 2019 - mdpi.com
Bifidobacteria typically represent the most abundant bacteria of the human gut microbiota in
healthy breast-fed infants. Members of the Bifidobacterium bifidum species constitute one of …

Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants

J Samara, S Moossavi, B Alshaikh, VA Ortega… - Cell host & …, 2022 - cell.com
Probiotics are increasingly administered to premature infants to prevent necrotizing
enterocolitis and neonatal sepsis. However, their effects on gut microbiome assembly and …

Key bacterial taxa and metabolic pathways affecting gut short-chain fatty acid profiles in early life

N Tsukuda, K Yahagi, T Hara, Y Watanabe… - The ISME …, 2021 - academic.oup.com
Infant gut microbiota development affects the host physiology throughout life, and short-
chain fatty acids (SCFAs) are promising key metabolites mediating microbiota-host …

Infant microbiome cultivation and metagenomic analysis reveal Bifidobacterium 2'-fucosyllactose utilization can be facilitated by coexisting species

YC Lou, BE Rubin, MC Schoelmerich… - Nature …, 2023 - nature.com
The early-life gut microbiome development has long-term health impacts and can be
influenced by factors such as infant diet. Human milk oligosaccharides (HMOs), an essential …

Human milk oligosaccharides modify the strength of priority effects in the Bifidobacterium community assembly during infancy

MF Laursen, HM Roager - The ISME Journal, 2023 - academic.oup.com
Despite the significant role of the gut microbiota in infant health and development, little is
known about the ecological processes determining gut microbial community assembly …

Strain-specific strategies of 2′-fucosyllactose, 3-fucosyllactose, and difucosyllactose assimilation by Bifidobacterium longum subsp. infantis Bi-26 and ATCC 15697

BE Zabel, S Gerdes, KC Evans, D Nedveck… - Scientific Reports, 2020 - nature.com
Human milk provides essential nutrients for infant nutrition. A large proportion of human milk
is composed of human milk oligosaccharides (HMOs), which are resistant to digestion by the …

Linking human milk oligosaccharide metabolism and early life gut microbiota: Bifidobacteria and beyond

C Lordan, AK Roche, D Delsing, A Nauta… - Microbiology and …, 2024 - Am Soc Microbiol
Human milk oligosaccharides (HMOs) are complex, multi-functional glycans present in
human breast milk. They represent an intricate mix of heterogeneous structures which reach …

Gut microbiota: A key role for human milk oligosaccharides in regulating host health early in life

Q Chen, X Ma, Z Guo, P Zhang, B Li… - … Reviews in Food …, 2024 - Wiley Online Library
Human milk oligosaccharides (HMOs) are an evolutionarily significant advantage bestowed
by mothers for facilitating the development of the infant's gut microbiota. They can avoid …

[PDF][PDF] Settlers of our inner surface–factors shaping the gut microbiota from birth to toddlerhood

MF Laursen, MI Bahl, TR Licht - FEMS Microbiology Reviews, 2021 - academic.oup.com
During the first 3 years of life, the microbial ecosystem within the human gut undergoes a
process that is unlike what happens in this ecosystem at any other time of our life. This …