Small animal models play a fundamental role in brain research by deepening the
understanding of the physiological functions and mechanisms underlying brain disorders …

Despite many ongoing efforts across the full spectrum of pharmaceutical and biotech
industries, drug development is still a costly undertaking that involves a high risk of failure …

Radiotracers are widely used to track molecular processes, both in vitro and in vivo, with
high sensitivity and specificity. However, most radionuclide detection methods have spatial …

Background & Aims Although nearly half of pancreatic ductal adenocarcinoma (PDAC)
patients have diabetes mellitus with episodes of hyperglycemia, its tumor microenvironment …

The investigation of molecular uptake and its kinetics in cells is valuable for understanding
the cellular physiological status, the observation of drug interventions, and the development …

Tracer kinetic modelling based on dynamic PET is an important field of Nuclear Medicine for
quantitative functional imaging. Yet, its implementation in clinical routine has been …

On-chip radiometric detection of biological samples using radiotracers has become an
emerging research field known as microfluidic radiobioassays. Performing parallel …

Pharmacokinetics (PK), as a significant part of pharmacology, runs through the overall
process of the preclinical and clinical research on drugs and plays a significant role in …

Integrated bioassay systems that combine microfluidics and radiation detectors can deliver
medical radiopharmaceuticals to live cells with precise timing, while minimizing radiation …

Radiopharmaceutical therapy (RPT) has shown great promise in the treatment of various
cancers. However, the current approach is a ''one size fits all” model, which results in varied …