Huntington's disease (HD) is the most common monogenic neurodegenerative disease and
the commonest genetic dementia in the developed world. With autosomal dominant …

Stem cells are the seeds of tissue repair and regeneration and a promising source for novel
therapies. However, apart from hematopoietic stem cell (HSC) transplantation, essentially all …

Degeneration of medium spiny GABA neurons in the basal ganglia underlies motor
dysfunction in Huntington's disease (HD), which presently lacks effective therapy. In this …

Huntington disease is a monogenic neurodegenerative disorder that displays an autosomal-
dominant pattern of inheritance. It is characterized by motor, psychiatric, and cognitive …

Induced pluripotent stem cells (iPSCs) generated from somatic cells of patients can be used
to model different human diseases. They may also serve as sources of transplantable cells …

Since 1928, human fetal tissues and stem cells have been used worldwide to treat various
conditions. Although the transplantation of the fetal midbrain substantia nigra and …

Huntington's disease (HD) is a rare inherited neurodegenerative disease that manifests
mostly in adulthood with progressive cognitive, behavioral, and motor dysfunction. Neuronal …

Huntington's disease (HD) is a fatal autosomal dominant neurodegenerative disease
involving progressive motor, cognitive and behavioural decline, leading to death …

Introduction Huntington's disease (HD) is the most common hereditary neurodegenerative
disorder. Despite the fact that both the gene and the mutation causing this monogenetic …

Huntington disease (HD) is an inherited, progressive neurological disorder characterized by
degenerating striatal medium spiny neurons (MSNs). One promising approach for treating …