Novel 2-aminopyridine liganded Pd (II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties

F Erdemir, DB Celepci, A Aktaş, Y Gök, R Kaya… - Bioorganic …, 2019 - Elsevier
In this work, the synthesis, crystal structure, characterization, and enzyme inhibition effects of
the novel a series of 2-aminopyridine liganded Pd (II) N-heterocyclic carbene (NHC) …

The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products

C Bayrak, P Taslimi, HS Karaman, I Gulcin… - Bioorganic chemistry, 2019 - Elsevier
Starting from vanillin, known four benzyl bromides with Br were synthesized. The first
synthesis of natural product 3, 4-dibromo-5-((methylsulfonyl) methyl) benzene-1, 2-diol (2) …

Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions

N Öztaskın, P Taslimi, A Maraş, İ Gülcin, S Göksu - Bioorganic chemistry, 2017 - Elsevier
In this study, a series of novel bromophenols were synthesized from benzoic acids and
methoxylated bromophenols. The synthesized compounds were evaluated by using different …

Synthesis of chalcone-imide derivatives and investigation of their anticancer and antimicrobial activities, carbonic anhydrase and acetylcholinesterase enzymes …

UM Kocyigit, Y Budak, MB Gürdere… - … of physiology and …, 2018 - Taylor & Francis
Abstract The new 1-(4-(3-(aryl) acryloyl) phenyl)-1H-pyrrole-2, 5-diones (5a–g) were
prepared from 4′-aminchalcones (3a–g) and screened for biological activities. All …

Synephrine and phenylephrine act as α‐amylase, α‐glycosidase, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase enzymes inhibitors

P Taslimi, H Akıncıoglu, İ Gülçin - Journal of biochemical and …, 2017 - Wiley Online Library
In this paper, synephrine and phenylephrine compounds showed excellent inhibitory effects
against human carbonic anhydrase (hCA) isoforms I and II, α‐amylase, α‐glycosidase …

Synthesis and biological evaluation of phloroglucinol derivatives possessing α‐glycosidase, acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase …

S Burmaoglu, AO Yilmaz, P Taslimi, O Algul… - Archiv Der …, 2018 - Wiley Online Library
A series of novel phloroglucinol derivatives were designed, synthesized, characterized
spectroscopically and tested for their inhibitory activity against selected metabolic enzymes …

Synthesis, characterization and crystal structure of 2-(4-hydroxyphenyl) ethyl and 2-(4-nitrophenyl) ethyl Substituted Benzimidazole Bromide Salts: Their inhibitory …

A Behcet, T Çağlılar, DB Celepci, A Aktaş… - Journal of Molecular …, 2018 - Elsevier
This paper reports the synthesis of 2-(4-hydroxyphenyl) ethyl and 2-(4-nitrophenyl) ethyl
substituted benzimidazolium salts. The benzimidazolium salts were synthesized by N …

Synthesis of diaryl ethers with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions

F Özbey, P Taslimi, İ Gülçin, A Maraş… - Journal of enzyme …, 2016 - Taylor & Francis
A series of diaryl ethers were synthesized and their human (h) carbonic anhydrase (CA)
isoenzymes hCA I and II, acetylcholinesterase (AChE), and butyrylcholinesterase (BuChE) …

Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors

İ Gulçin, M Abbasova, P Taslimi, Z Huyut… - Journal of enzyme …, 2017 - Taylor & Francis
Compounds containing nitrogen and sulfur atoms can be widely used in various fields such
as industry, medicine, biotechnology and chemical technology. Therefore, the reactions of …

Anticancer and antimicrobial activities of new thiazolyl-urea derivatives: gene expression, DNA damage, DNA fragmentation and SAR studies

FM Sroor, AM Othman, MM Aboelenin… - Medicinal Chemistry …, 2022 - Springer
The drug resistance became the major challenge in the antimicrobial and anticancer drugs
therapy. Therefore, there is an urgent need to looking for new types of antimicrobial and …