Camptothecin (CPT) and its derivatives comprise an important group of heterocyclic
compounds that are well recognized for their anticancer activities. Efforts have been made …

Mycobacterium tuberculosis is the single most important global infectious disease killer and
a World Health Organization critical priority pathogen for development of new antimicrobials …

A transition metal‐free, regioselective C‐5 trifluoromethylation of 2, 3‐dihydropyridin‐4 (1H)‐
ones (cyclic enaminones) with trimethyl (trifluoromethyl) silane (TMSCF3) was developed …

Quinolones (oxo-quinolines) are a versatile sub-group within the quinoline family with
potential applications in major fields, namely in medicine. Several quinolone-derived …

We have recently developed a 2P2IHUNTER learning machine tool for filtering potential
orthosteric PPI modulators. In the present research article we applied our algorithm to 8.3 …

With the aim of discovering new anticancer agents, we have designed and synthesized
novel 6-hydroxy-benzo [d][1, 3] oxathiol-2-one Schiff bases. The synthesis started with the …

In this work, we report the synthesis and antitubercular activity of sixteen fluoroquinolones
analogs of Cipro-, Gati-, Moxi-, and Gemifloxacin coupled with the terpenes, prenol …

摘要目的: 建立加替沙星注射液无菌检查方法. 方法: 根据《 中国药典》 2010 年版二部附录XI H
无菌检查法验证试验指导原则, 采用薄膜过滤法和添加硫酸锰中和剂去除加替沙星抑菌活性的 …

A systematized review of reviews and monographs published in 2012–2013 on all aspects
of heterocyclic chemistry is given.

A series of ethyl (substituted) phenyl‐4‐oxothiazolidin‐3‐yl)‐1‐ethyl‐4‐oxo‐1, 4‐
dihydroquinoline‐3‐carboxylates (7a, 7b, 7c, 7d, 7e, 7f, 7g) has been prepared from …