Emerging and future strategies in the management of recalcitrant Candida auris

N Bandara, L Samaranayake - Medical Mycology, 2022 - academic.oup.com
Candida auris is an emerging, multi drug resistant fungal pathogen that has caused
infectious outbreaks in over 45 countries since its first isolation over a decade ago, leading …

Drug repurposing against Candida auris: A systematic review

A Izadi, S Aghaei Gharehbolagh, F Sadeghi… - Mycoses, 2022 - Wiley Online Library
Candida auris is a drug‐resistant pathogen with several reported outbreaks. The treatment
of C. auris infections is difficult due to a limited number of available antifungal drugs. Thus …

Recent advances and future perspectives in the pharmacological treatment of Candida auris infections

DR Giacobbe, L Magnasco, C Sepulcri… - Expert Review of …, 2021 - Taylor & Francis
Introduction Candida auris is responsible for hospital outbreaks worldwide. Some C. auris
isolates may show concomitant resistance to azoles, echinocandins, and polyenes, thereby …

Accumulation of endogenous free radicals is required to induce titan-like cell formation in Cryptococcus neoformans

I García-Barbazán, A Torres-Cano, R García-Rodas… - Mbio, 2024 - Am Soc Microbiol
Cryptococcus neoformans is an encapsulated yeast able to cause disease (mainly
meningoencephalitis) among immunosuppressed patients, mostly HIV+. This yeast can form …

Novel avenues for identification of new antifungal drugs and current challenges

J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Some of the fungi have become pathogenic to humans, and these opportunistic
pathogens are able to cause severe systemic mycoses. Areas covered The number of …

Screening the medicine for malaria venture's Pandemic Response Box to identify novel inhibitors of Candida albicans and Candida auris biofilm formation

OH Ajetunmobi, AK Chaturvedi, H Badali, A Vaccaro… - APMIS, 2023 - Wiley Online Library
Candida spp. are opportunistic yeasts capable of forming biofilms, which contribute to
resistance, increasing the urgency for new effective antifungal therapies. Repurposing …

The Potential of Dutasteride for Treating Multidrug-Resistant Candida auris Infection

JF Borgio, NB Almandil, P Selvaraj, JS John… - Pharmaceutics, 2024 - mdpi.com
Novel antifungal drugs are urgently needed to treat candidiasis caused by the emerging
fungal multidrug-resistant pathogen Candida auris. In this study, the most cost-effective drug …

High-Throughput Screening of the Repurposing Hub Library to Identify Drugs with Novel Inhibitory Activity against Candida albicans and Candida auris Biofilms

OH Ajetunmobi, G Wall, B Vidal Bonifacio… - Journal of Fungi, 2023 - mdpi.com
Candidiasis is one of the most frequent nosocomial infections affecting an increasing
number of at-risk patients. Candida albicans remains the most frequent causative agent of …

Prospective Medicines against the Widespread, Emergent, and Multidrugresistant Opportunistic Fungal Pathogen Candida auris: A Breath of Hope

LS Ramos, LN Silva, TP de Mello… - Current Topics in …, 2022 - ingentaconnect.com
The emergence of the pathogen Candida auris is a real concern worldwide, especially due
to its multidrug resistance profile, besides the difficulties in establishing the correct …

[PDF][PDF] Candida auris. Una levadura patógena de emergencia exponencial

MTC de Simón - Anales de la Real Academia de Doctores, 2022 - rade.es
RESUMEN Candida auris (C. auris), es un patógeno emergente a nivel mundial que está
provocando desconcertantes y exponenciales episodios de graves infecciones en …