Melatonin and human cardiovascular disease

SR Pandi-Perumal, AS BaHammam… - Journal of …, 2017 - journals.sagepub.com
The possible therapeutic role of melatonin in the pathophysiology of coronary artery disorder
(CAD) is increasingly being recognized. In humans, exogenous melatonin has been shown …

Cardiovascular effects of melatonin receptor agonists

L Paulis, F Simko, M Laudon - Expert opinion on investigational …, 2012 - Taylor & Francis
Introduction: Melatonin synchronizes circadian rhythms with light/dark period and it was
demonstrated to correct chronodisruption. Several melatonin receptor agonists with …

MT2 melatonin receptors are present and functional in rat caudal artery

MI Masana, S Doolen, C Ersahin, WM Al-Ghoul… - … of Pharmacology and …, 2002 - ASPET
In rat caudal artery, contraction to melatonin results primarily from activation of MT1
melatonin receptors; however, the role of MT2 melatonin receptors in vascular responses is …

Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation

CMC Lotufo, C Lopes, ML Dubocovich… - European journal of …, 2001 - Elsevier
The hormone melatonin produced by the pineal gland during the daily dark phase regulates
a variety of biological processes in mammals. The aim of this study was to determine the …

The role of melatonin in alleviating the postharvest browning of lotus seeds through energy metabolism and membrane lipid metabolism

S Luo, H Hu, Y Wang, H Zhou, Y Zhang… - Postharvest Biology and …, 2020 - Elsevier
To investigate the underlying mechanism of melatonin (MT) involvement in the browning of
lotus pods and seeds, the samples were immersed in 100 μmol L− 1 MT and 10 μmol L− 1 …

EXPRESSION OF THE MT1 MELATONIN RECEPTOR SUBTYPE IN HUMAN CORONARY ARTERIES

C Ekmekcioglu, P Haslmayer, C Philipp… - Journal of Receptors …, 2001 - Taylor & Francis
Previous experimental data suggest a possible influence of melatonin on the circulatory
system of animals after binding to G-protein coupled melatonin receptors. The present study …

Inhibitory effects of melatonin on vascular reactivity: possible role of vasoactive mediators

MM Anwar, ARMA Meki, HHA Rahma - Comparative Biochemistry and …, 2001 - Elsevier
Melatonin (MEL), the principal hormone of the vertebral pineal gland, elicits several
neurobiological effects. However, the effects of MEL on vascular tissues are still vague. The …

Melatonin inhibits endothelial nitric oxide production in vitro

EK Tamura, CLM Silva, RP Markus - Journal of pineal research, 2006 - Wiley Online Library
Endothelial cell function is a major player on the regulation of both vascular tonus and
permeability. Activation of nitric oxide synthase (NOS) by bradykinin is one physiological …

CARDIOVASCULAR ACTIONS OF THE VENOM FROM THE IRUKANDJI (CARUKIA BARNESI) JELLYFISH: EFFECTS IN HUMAN, RAT AND GUINEA‐PIG TISSUES IN VITRO …

KD Winkel, J Tibballs, P Molenaar… - Clinical and …, 2005 - Wiley Online Library
We have investigated the cardiovascular pharmacology of the crude venom extract (CVE)
from the potentially lethal, very small carybdeid jellyfish Carukia barnesi, in rat, guinea‐pig …

Antioxidant melatonin: potential functions in improving cerebral autoregulation after subarachnoid hemorrhage

ZN Guo, H Jin, H Sun, Y Zhao, J Liu, H Ma… - Frontiers in …, 2018 - frontiersin.org
Subarachnoid hemorrhage (SAH) is a subtype of stroke with high mortality and morbidity.
Impaired cerebral autoregulation following SAH has been reported owing to effects on …