Conspectus Over the past decades, major efforts were undertaken to develop devices on a
nanoscale level for the efficient and nontoxic delivery of molecules to tissues and cells, for …

Smart drug delivery systems (DDSs) have attracted the attention of many scientists, as
carriers that can be stimulated by changes in environmental parameters such as …

How various macromolecules are exchanged between cells and how they gain entry into
recipient cells are fundamental questions in cell biology with important implications eg non …

Lipoplexes and polyplexes are widely applied as nonviral gene delivery carriers. Although
their efficiencies of transfection are comparable, their mechanisms of delivery, specifically at …

Cationic lipid-and polymer-based nanodevices are considered appropriate alternatives for
virus-based particles for delivery of nucleic acids, including genes and siRNA, into …

Three decades have passed from the initial discovery of a microRNA (miRNA) in
Caenorhabditis elegans to our current understanding that miRNAs play essential roles in …

Liposomes are one of the most widely investigated carriers for CRISPR/Cas9 delivery. The
surface properties of liposomal carriers, including the surface charge, PEGylation, and …

Polyplex-mediated gene transfection is now in its' fourth decade of serious research, but the
promise of polyplex-mediated gene therapy has yet to fully materialize. Only approximately …

Drug delivery to the brain is greatly hampered by the presence of the blood–brain barrier
(BBB) which tightly regulates the passage of molecules from blood to brain and vice versa …

Simple Summary Cell migration is crucial fReaor metastasis formation and a hallmark of
malignancy. The primary cause of high mortality among oncology patients is the ability of …