[HTML][HTML] Genetic landscape of common epilepsies: advancing towards precision in treatment
Epilepsy, a neurological disease characterized by recurrent seizures, is highly
heterogeneous in nature. Based on the prevalence, epilepsy is classified into two types …
heterogeneous in nature. Based on the prevalence, epilepsy is classified into two types …
ILAE definition of the idiopathic generalized epilepsy syndromes: position statement by the ILAE task force on nosology and definitions
Abstract In 2017, the International League Against Epilepsy (ILAE) Classification of
Epilepsies described the “genetic generalized epilepsies”(GGEs), which contained the …
Epilepsies described the “genetic generalized epilepsies”(GGEs), which contained the …
Targeting metabotropic glutamate receptors in the treatment of epilepsy: rationale and current status
R Celli, I Santolini, G Van Luijtelaar… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Several drugs targeting the GABAergic system are used in the treatment of
epilepsy, but only one drug targeting glutamate receptors is on the market. This is surprising …
epilepsy, but only one drug targeting glutamate receptors is on the market. This is surprising …
[HTML][HTML] SLCO5A1 and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsy
D Roshandel, EJ Sanders, A Shakeshaft… - npj Genomic …, 2023 - nature.com
Elevated impulsivity is a key component of attention-deficit hyperactivity disorder (ADHD),
bipolar disorder and juvenile myoclonic epilepsy (JME). We performed a genome-wide …
bipolar disorder and juvenile myoclonic epilepsy (JME). We performed a genome-wide …
Diagnostic and therapeutic approach to drug-resistant juvenile myoclonic epilepsy
M Ascoli, G Mastroianni, S Gasparini… - Expert review of …, 2021 - Taylor & Francis
Introduction Juvenile myoclonic epilepsy (JME), also known as Janz syndrome, is a common
form of generalized epilepsy of presumed genetic origin representing up to 10% of all …
form of generalized epilepsy of presumed genetic origin representing up to 10% of all …
DNA methylation of the BRD2 promoter is associated with juvenile myoclonic epilepsy in Caucasians
S Pathak, J Miller, EC Morris, WCL Stewart… - …, 2018 - Wiley Online Library
Objective Juvenile myoclonic epilepsy (JME) is a common adolescent‐onset genetic
generalized epilepsy (GGE) syndrome. Multiple linkage and association studies have found …
generalized epilepsy (GGE) syndrome. Multiple linkage and association studies have found …
[HTML][HTML] Multi-gene panel testing in Korean patients with common genetic generalized epilepsy syndromes
CG Lee, J Lee, M Lee - PLoS One, 2018 - journals.plos.org
Genetic heterogeneity of common genetic generalized epilepsy syndromes is frequently
considered. The present study conducted a focused analysis of potential candidate or …
considered. The present study conducted a focused analysis of potential candidate or …
[HTML][HTML] Juvenile myoclonic epilepsy has hyper dynamic functional connectivity in the dorsolateral frontal cortex
Y Wang, IS Berglund, M Uppman, TQ Li - NeuroImage: Clinical, 2019 - Elsevier
Purpose Characterize the static and dynamic functional connectivity for subjects with
juvenile myoclonic epilepsy (JME) using a quantitative data-driven analysis approach …
juvenile myoclonic epilepsy (JME) using a quantitative data-driven analysis approach …
A systematic review of resting-state and task-based fmri in juvenile myoclonic epilepsy
H Sanjari Moghaddam, A Sanjari Moghaddam… - Brain imaging and …, 2022 - Springer
Functional neuroimaging modalities have enhanced our understanding of juvenile
myoclonic epilepsy (JME) underlying neural mechanisms. Due to its non-invasive, sensitive …
myoclonic epilepsy (JME) underlying neural mechanisms. Due to its non-invasive, sensitive …
[HTML][HTML] A systematic review and meta-analysis of factors related to first line drugs refractoriness in patients with juvenile myoclonic epilepsy (JME)
Introduction Juvenile Myoclonic Epilepsy (JME) is a prevalent form of epileptic disorder,
specifically categorized within the realm of Genetic Generalized Epilepsy (GGE). Its hallmark …
specifically categorized within the realm of Genetic Generalized Epilepsy (GGE). Its hallmark …