Liver cancer is a global health challenge, causing a significant social-economic burden.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …

High mobility group box 1 (HMGB1) is an extremely versatile protein that is located
predominantly in the nucleus of quiescent eukaryotic cells, where it is critically involved in …

Background Increasing evidence suggests that taurine upregulated gene 1 (TUG1) is crucial
for tumor progression; however, its role in hepatocellular carcinoma (HCC) and the …

Hepatocellular carcinoma (HCC), is the third leading cause of cancer-related deaths, which
is largely caused by virus infection. About 80% of the virus-infected people develop a …

Hepatocellular carcinoma (HCC) is a complex and heterogeneous malignancy with high
incidence and poor prognosis. In addition, owing to the lack of diagnostic and prognostic …

Background & Aims Patients with HCV who achieve a sustained virological response (SVR)
on direct-acting antiviral (DAA) therapy still need to be monitored for signs of liver disease …

Disorders of miR-484 expression are observed in cancer, different diseases or pathological
states. There is accumulating evidence that miR-484 plays an essential role in the …

Digital polymerase chain reaction (dPCR) is a mature technique that has enabled scientific
breakthroughs in several fields. However, this technology is primarily used in research …

Chronic hepatitis C virus (cHCV) is a leading cause for liver cirrhosis (LC) and
hepatocellular carcinoma (HCC) globally. So far, there is no optimal non-invasive biomarker …

Liver biopsy is historically the gold standard for liver fibrosis assessment of chronic hepatitis
C patients. However, with the introduction and validation of noninvasive tests (NITs) to …