Two decades ago successful transfection of antigen presenting cells (APC) in vivo was
demonstrated which resulted in the induction of primary adaptive immune responses. Due to …

Research on tumor immunotherapy has made tremendous progress in the past decades,
with numerous studies entering the clinical evaluation. The cancer vaccine is considered a …

The recent developments in immuno-oncology have opened an unprecedented avenue for
the emergence of vaccine strategies. Therapeutic DNA cancer vaccines are now considered …

Vaccination was first pioneered in the 18th century by Edward Jenner and eventually led to
the development of the smallpox vaccine and subsequently the eradication of smallpox. The …

The development of therapeutic cancer vaccines as a means to generate immune reactivity
against tumors has been explored since the early discovery of tumor-specific antigens by …

Today, it is well-known that the interactions and secretion within the tumour are crucial to
consider for cancer therapy. Some novel cancer therapy modalities such as immunotherapy …

Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The
conventional treatment options for cancer have numerous challenges, such as a low blood …

Immunotherapy has recently emerged as a powerful tool for cancer treatment. Early clinical
successes from cancer immunotherapy have led to a growing list of FDA approvals, and …

Immunotherapy is a new type of tumor treatment after surgery, radiotherapy and
chemotherapy, which can be used to manage and destroy tumor cells through activating or …

With the approval of the first therapeutic cancer vaccine by US Food and Drug
Administration, numerous therapeutic cancer vaccines have been under clinical trials with …