Busting the myth of methotrexate chronic hepatotoxicity

V Di Martino, DW Verhoeven, F Verhoeven… - Nature Reviews …, 2023 - nature.com
Methotrexate is a key component of the treatment of inflammatory rheumatic diseases and
the mainstay of therapy in rheumatoid arthritis. Hepatotoxicity has long been a concern for …

[HTML][HTML] Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated

E Atallah, JI Grove, C Crooks, E Burden-Teh… - Journal of …, 2023 - Elsevier
Background & Aims The risk of significant liver fibrosis from prolonged methotrexate (MTX)
exposure has been estimated at around 5%, prompting intensive monitoring strategies …

International eDelphi study to reach consensus on the methotrexate dosing regimen in patients with psoriasis

AM Van Huizen, SP Menting, R Gyulai… - JAMA …, 2022 - jamanetwork.com
Importance A clear dosing regimen for methotrexate in psoriasis is lacking, and this might
lead to a suboptimal treatment. Because methotrexate is affordable and globally available, a …

Fatty liver disease that is neither metabolic nor alcoholic

DS Allende, DE Kleiner - Human Pathology, 2023 - Elsevier
Fatty liver disease that is neither metabolic nor alcoholic - ScienceDirect Skip to main
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[HTML][HTML] One-step detection of procollagen type III N-terminal peptide as a fibrosis biomarker using fluorescent immunosensor (Quenchbody)

JY Yi, J Ryu, Y Jeong, Y Cho, M Kim, M Jeon… - Analytica Chimica …, 2024 - Elsevier
Abstract Background Procollagen type III N-terminal peptide (P-III-NP) is a fibrosis biomarker
associated with liver and cardiac fibrosis. Despite the value of P-III-NP as a biomarker, its …

Longitudinal assessment of liver stiffness using ARFI technique does not support increased risk of fibrosis in rheumatoid arthritis patients on methotrexate

A Schäfer, MS Kovacs, A Eder, A Nigg… - Journal of …, 2024 - Springer
Aims To assess the liver stiffness in patients with rheumatoid arthritis treated with
methotrexate monotherapy using non-invasive, ultrasound-based elastography (acoustic …

Sonoelastography: A powerful technique in musculoskeletal imaging

WL Sibbitt Jr, RR Sibbitt - Journal of Clinical Ultrasound, 2023 - Wiley Online Library
Sonoelastography is a powerful method available to observe the musculoskeletal system,
and appears particularly valuable in detecting early tendinopathies, pursuing complaints of …

Machine learning and magnetic resonance imaging: Differentiating benign from malignant osseous tumors

NS Emil, RR Sibbitt, WL Sibbitt Jr - Journal of Clinical …, 2023 - Wiley Online Library
Radiomics and machine learning applied to the isolated cartilaginous bone lesion on
magnetic resonance imaging (MRI) is increasingly useful to distinguish malignant versus …