Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

[HTML][HTML] Cell or cell membrane-based drug delivery systems

S Tan, T Wu, D Zhang, Z Zhang - Theranostics, 2015 - ncbi.nlm.nih.gov
Natural cells have been explored as drug carriers for a long period. They have received
growing interest as a promising drug delivery system (DDS) until recently along with the …

Nitroxide-based macromolecular contrast agents with unprecedented transverse relaxivity and stability for magnetic resonance imaging of tumors

HVT Nguyen, Q Chen, JT Paletta, P Harvey… - ACS Central …, 2017 - ACS Publications
Metal-free magnetic resonance imaging (MRI) agents could overcome the established
toxicity associated with metal-based agents in some patient populations and enable new …

A multifunctional magnetic red blood cell-mimetic micromotor for drug delivery and image-guided therapy

K Hou, Y Zhang, M Bao, C Xin, Z Wei… - ACS applied materials …, 2022 - ACS Publications
Inspired by nature, innovative devices have been made to imitate the morphology and
functions of natural red blood cells (RBCs). Here, we report a red blood cell-mimetic …

Remotely controlled red blood cell carriers for cancer targeting and near‐infrared light‐triggered drug release in combined photothermal–chemotherapy

X Sun, C Wang, M Gao, A Hu… - Advanced Functional …, 2015 - Wiley Online Library
Red blood cells (RBCs), the “innate carriers” in blood vessels, are gifted with many unique
advantages in drug transportation over synthetic drug delivery systems (DDSs). Herein, a …

[HTML][HTML] Erythrocytes as carriers: From drug delivery to biosensors

L Koleva, E Bovt, F Ataullakhanov, E Sinauridze - Pharmaceutics, 2020 - mdpi.com
Drug delivery using natural biological carriers, especially erythrocytes, is a rapidly
developing field. Such erythrocytes can act as carriers that prolong the drug's action due to …

Advances in magnetic resonance imaging contrast agents for biomarker detection

S Sinharay, MD Pagel - Annual Review of Analytical Chemistry, 2016 - annualreviews.org
Recent advances in magnetic resonance imaging (MRI) contrast agents have provided new
capabilities for biomarker detection through molecular imaging. MRI contrast agents based …

[HTML][HTML] MRI contrast agents in glycobiology

CFGC Geraldes, JA Peters - Molecules, 2022 - mdpi.com
Molecular recognition involving glycoprotein-mediated interactions is ubiquitous in both
normal and pathological natural processes. Therefore, visualization of these interactions …

LipoCEST and cellCEST imaging agents: opportunities and challenges

G Ferrauto, D Delli Castelli… - Wiley …, 2016 - Wiley Online Library
From the early days of CEST agents' disclosure, it was evident that their potential for in vivo
applications was strongly hampered by the intrinsic low sensitivity. Therefore, much work …

Biomimetic surface modification of discoidal polymeric particles

TDT Nguyen, S Aryal, A Pitchaimani, S Park… - … , Biology and Medicine, 2019 - Elsevier
The rationale for the design of drug delivery nanoparticles is traditionally based on co-
solvent self-assembly following bottom-up approaches or in combination with top-down …