Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update

A Rodriguez-Mateos, D Vauzour, CG Krueger… - Archives of …, 2014 - Springer
There is substantial interest in the role of plant secondary metabolites as protective dietary
agents. In particular, the involvement of flavonoids and related compounds has become a …

Combinatorial epigenetics impact of polyphenols and phytochemicals in cancer prevention and therapy

I Arora, M Sharma, TO Tollefsbol - International journal of molecular …, 2019 - mdpi.com
Polyphenols are potent micronutrients that can be found in large quantities in various food
sources and spices. These compounds, also known as phenolics due to their phenolic …

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

Gallic acid attenuates angiotensin II-induced hypertension and vascular dysfunction by inhibiting the degradation of endothelial nitric oxide synthase

X Yan, QY Zhang, YL Zhang, X Han, SB Guo… - Frontiers in …, 2020 - frontiersin.org
Hypertension is a major cause of heart attack and stroke. Our recent study revealed that
gallic acid (GA) exerts protective effects on pressure overload-induced cardiac hypertrophy …

An overview of epigenetic agents and natural nutrition products targeting DNA methyltransferase, histone deacetylases and microRNAs

D Huang, LQ Cui, S Ahmed, F Zainab, Q Wu… - Food and Chemical …, 2019 - Elsevier
Several humans' diseases such as; cancer, heart disease, diabetes retain an etiology of
epigenetic, and a new therapeutic option termed as “epigenetic therapy” can offer a potential …

Protective effect of the curcumin-baicalein combination against macrovascular changes in diabetic angiopathy

C Wang, Y Sun, W Liu, Y Liu, S Afzal… - Frontiers in …, 2022 - frontiersin.org
Endothelial dysfunction is an early pathological event in diabetic angiopathy which is the
most common complication of diabetes. This study aims to investigate individual and …

Advances in the Study of Vascular Protective Effects and Molecular Mechanisms of Mulberry

J Hao, M Lu, J Li, X Guan, W Yang, R Sun… - Food Reviews …, 2024 - Taylor & Francis
Mulberry is the fruit of Morus alba L, family Moraceae. The dried fruit spikes of Morus alba L,
is a widely used herbal medicine with a variety of bioactive substances, including …

Roseltide rT7 is a disulfide-rich, anionic, and cell-penetrating peptide that inhibits proteasomal degradation

A Kam, S Loo, JS Fan, SK Sze, D Yang… - Journal of Biological …, 2019 - ASBMB
Disulfide-rich plant peptides with molecular masses of 2–6 kDa represent an expanding
class of peptidyl-type natural products with diverse functions. They are structurally compact …

Protective roles and therapeutic effects of gallic acid in the treatment of cardiovascular diseases: current trends and future directions

Z Momeni, S Danesh, M Ahmadpour… - Current Medicinal …, 2024 - benthamdirect.com
Cardiovascular diseases (CVDs) are serious life-threatening illnesses and significant
problematic issues for public health having a heavy economic burden on all society …

Synergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA. hy926 cells

X Zhou, V Razmovski-Naumovski, A Kam… - … and alternative medicine, 2019 - Springer
Background This study investigated the protective effects of the Danshen (DS) and Sanqi
(SQ) herb pair on cell survival in the human cardiovascular endothelial (EA. hy926) cell line …