Vitamin D binding protein: a multifunctional protein of clinical importance
MM Speeckaert, R Speeckaert, N van Geel… - Advances in clinical …, 2014 - Elsevier
Since the discovery of group-specific component and its polymorphism by Hirschfeld in
1959, research has put spotlight on this multifunctional transport protein (vitamin D binding …
1959, research has put spotlight on this multifunctional transport protein (vitamin D binding …
[HTML][HTML] Pathogenesis and management of Brugada syndrome: recent advances and protocol for umbrella reviews of meta-analyses in major arrhythmic events risk …
HM Aziz, MP Zarzecki, S Garcia-Zamora… - Journal of Clinical …, 2022 - mdpi.com
Brugada syndrome (BrS) is a primary electrical disease associated with life-threatening
arrhythmias. It is estimated to cause at least 20% of sudden cardiac deaths (SCDs) in …
arrhythmias. It is estimated to cause at least 20% of sudden cardiac deaths (SCDs) in …
[HTML][HTML] Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy
C Talarico, L D'Antona, D Scumaci, A Barone… - Oncotarget, 2015 - ncbi.nlm.nih.gov
The SGK1 kinase is pivotal in signal transduction pathways operating in cell transformation
and tumor progression. Here, we characterize in depth a novel potent and selective pyrazolo …
and tumor progression. Here, we characterize in depth a novel potent and selective pyrazolo …
A vital role for complement in heart disease
Heart diseases are common and significant contributors to worldwide mortality and
morbidity. During recent years complement mediated inflammation has been shown to be an …
morbidity. During recent years complement mediated inflammation has been shown to be an …
[HTML][HTML] DJ-1 proteoforms in breast cancer cells: The escape of metabolic epigenetic misregulation
D Scumaci, E Olivo, CV Fiumara, M La Chimia… - Cells, 2020 - mdpi.com
Enhanced glycolysis is a hallmark of breast cancer. In cancer cells, the high glycolytic flux
induces carbonyl stress, a damaging condition in which the increase of reactive carbonyl …
induces carbonyl stress, a damaging condition in which the increase of reactive carbonyl …
[HTML][HTML] Brugada syndrome: warning of a systemic condition?
S D'Imperio, MM Monasky, E Micaglio… - Frontiers in …, 2021 - frontiersin.org
Brugada syndrome (BrS) is a hereditary disorder, characterized by a specific
electrocardiogram pattern and highly related to an increased risk of sudden cardiac death …
electrocardiogram pattern and highly related to an increased risk of sudden cardiac death …
[HTML][HTML] Evaluating the use of genetics in brugada syndrome risk stratification
MM Monasky, E Micaglio, ET Locati… - Frontiers in …, 2021 - frontiersin.org
The evolution of the current dogma surrounding Brugada syndrome (BrS) has led to a
significant debate about the real usefulness of genetic testing in this syndrome. Since BrS is …
significant debate about the real usefulness of genetic testing in this syndrome. Since BrS is …
[HTML][HTML] Review of liquid chromatography-mass spectrometry-based proteomic analyses of body fluids to diagnose infectious diseases
H Lee, SI Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
Rapid and precise diagnostic methods are required to control emerging infectious diseases
effectively. Human body fluids are attractive clinical samples for discovering diagnostic …
effectively. Human body fluids are attractive clinical samples for discovering diagnostic …
The omics of channelopathies and cardiomyopathies: what we know and how they are useful
C Pappone, E Micaglio, ET Locati… - European Heart …, 2020 - academic.oup.com
Sudden cardiac death results from arrhythmias commonly caused by channelopathies and
cardiomyopathies, often due to several genetic factors. An emerging concept is that these …
cardiomyopathies, often due to several genetic factors. An emerging concept is that these …
Biological sample collection for clinical proteomics: existing SOPs
V Lygirou, M Makridakis, A Vlahou - Clinical Proteomics: Methods and …, 2015 - Springer
Proteomic study of clinical samples aims at the better understanding of physiological and
pathological conditions, as well as the discovery of diagnostic and prognostic markers for …
pathological conditions, as well as the discovery of diagnostic and prognostic markers for …